Synoplus

by NewtonEverett · tablet or pill · 100 vegetarian tablets

  • On the market (NIH)
  • UPC 8 18423 02785 2
  • DSLD label 248872
  • Serving 2 vegetarian tablets
  • 50 servings

Synoplus by NewtonEverett lists 4 ingredients, 2 with an amount per serving of 2 vegetarian tablets, such as 1.5 g of glucosamine hydrochloride and 3.3 mg of hyaluronic acid; 2 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on May 22, 2021.

What is in Synoplus?

Each row as the label prints it, per serving of 2 vegetarian tablets. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Synoplus: Supplement Facts rows against the market (DSLD label 248872, January 2026 release)
IngredientAmount% DVAmong products listing it
Glucosamine HydrochlorideGlucosamine Hydrochloride Note: 1500 mg1.5 gGlucosamine Hydrochloride in Synoplus against 628 products1.5 g per serving; the middle half of products list 0.75 g to 1.5 g, the median 1.5 g.1.5 g

5% of 628 products listing glucosamine hydrochloride give more (median 1.5 g). Per day at the most servings: 3 g.

Hyaluronic Acid3.3 mgHyaluronic acid in Synoplus against 900 products3.3 mg per serving; the middle half of products list 10 mg to 100 mg, the median 50 mg.3.3 mg

85% of 900 products listing hyaluronic acid give more (median 50 mg). Per day at the most servings: 6.6 mg.

Synoflex Proprietary Herbal Extract250 mg
Chinese Skullcapin the blend, no amount given
Black Catechuin the blend, no amount given

Source: NIH ODS Dietary Supplement Label Database, label 248872 (entered May 22, 2021), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 85% of the 900 products that print an amount of hyaluronic acid list more than its 3.3 mg of hyaluronic acid (median 50 mg).

The NIH database records 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Synoplus's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Use: For best results, for the first 30 days take 2 tablets twice a day with meals (for a total of 4 tablets per day). After day 30, take 2 tablets once a day with a meal (for a total of 2 tablets per day).
Warnings
Contains: Shellfish (lobster, shrimp, crab).
Warning: Not for use by persons under the age of 18.
If pregnant nursing or taking a prescription drug, consult health care practitioner prior to use.
Keep out of reach of children.
Do not use if safety seal is damaged or missing.
Allergens and what it does not contain
Non-GMO Gluten free

Source: label statements in DSLD label 248872.

What else is on the label?

Other ingredients: Microcrystalline Cellulose, Vegetable Magnesium Stearate, Silicon Dioxide, Stearic Acid, Vegetable Coating, Titanium Dioxide.

How many labels does Synoplus have?

3 labels are on file under this name since June 25, 2014: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 248872 (current) Entered May 22, 2021 · on the market · 100 vegetarian tablets · UPC 8 18423 02785 2
  2. Label 213126 Entered January 25, 2020 · off the market April 9, 2021 · 100 tablets · UPC 8 18423 02785 2
  3. Label 34628 Entered June 25, 2014 · off the market May 15, 2019 · 100 tablets · UPC 6 89076 00413 8

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Newton-Everett Nutraceuticals (distributor), Scottsdale, AZ. All NewtonEverett products.

Where next?