St. John's Wort

by Nature's Sunshine · tablet or pill · 60 tablets

  • On the market (NIH)
  • UPC 0 99904 00653 9
  • DSLD label 278279
  • Serving 1 tablet
  • 60 servings

St. John's Wort by Nature's Sunshine lists one ingredient: 460 mg of St. John's wort aerial parts extract per serving of 1 tablet. Its current label entered the NIH Dietary Supplement Label Database on October 24, 2022.

What is in St. John's Wort?

Each row as the label prints it, per serving of 1 tablet. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

St. John's Wort: Supplement Facts rows against the market (DSLD label 278279, January 2026 release)
IngredientAmount% DVAmong products listing it
St. John's Wort aerial parts extractas Hyperforin, Hypericin460 mgSt. John's Wort in St. John's Wort against 338 products460 mg per serving; the middle half of products list 250 mg to 450 mg, the median 300 mg.460 mg

Higher than 76% of 338 products listing St. John's wort (median 300 mg). Per day at the most servings: 920 mg.

Source: NIH ODS Dietary Supplement Label Database, label 278279 (entered October 24, 2022), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records 1 to 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommended use: Take 1 tablet in the morning and one in the evening with water for all-day, all-night support.
Warnings
Warning: Do not use St. John's Wort while taking any prescription drugs without the advice of your prescribing physician. Do not use with prescription antidepressants, contraceptives, immunosuppressants, anticoagulants, Digoxin, blood thinners, or medications for HIV, epilepsy, or cancer.
Avoid excessive exposure to UV radiation (e.g. sunlight, tanning).
Not recommended for use by pregnant or lactating women.
Keep out of the reach of children.
Do not use if inner seal is missing or damaged.

Source: label statements in DSLD label 278279.

What else is on the label?

Other ingredients: Cellulose, Di-Calcium Phosphate, Stearic Acid, Magnesium Stearate.

How many labels does St. John's Wort have?

4 labels are on file under this name since January 25, 2012: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 278279 (current) Entered October 24, 2022 · on the market · 60 tablets · UPC 0 99904 00653 9
  2. Label 255489 Entered September 24, 2021 · on the market · 100 capsules · UPC 0 99904 00655 3
  3. Label 17752 Entered January 25, 2013 · off the market February 27, 2019 · 60 tablets · UPC 0 99904 00653 9
  4. Label 4495 Entered January 25, 2012 · off the market January 1, 2012 · 60 tablets · UPC 0 99904 00653 9

DSLD also links this label to: St. John's Wort Time Release (image difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Nature's Sunshine Products, Inc. (manufacturer), Spanish Fork, UT. All Nature's Sunshine products.

Where next?