Sleep-Assure With Botanical Extracts & Essential Cofactors
by Nature's Plus · tablet or pill · 60 bilayer tablets
- Off the market since July 2015 (NIH)
- UPC 0 97467 04760 0
- DSLD label 13399
- Serving 1 tablet
Sleep-Assure With Botanical Extracts & Essential Cofactors by Nature's Plus lists 3 ingredients, 3 with an amount per serving of 1 tablet, such as 10 mg of GABA, 5 mg of pyridoxal 5-phosphate and 3 mg of melatonin. Its current label entered the NIH Dietary Supplement Label Database on October 1, 2012.
What is in Sleep-Assure With Botanical Extracts & Essential Cofactors?
Each row as the label prints it, per serving of 1 tablet. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).
| Ingredient | Amount | % DV | Among products listing it |
|---|---|---|---|
| Herbal Blendas Chamomile, Passionflower, ValerianHerbal Blend (Form: equal proportions of Passionflower Flower PlantPart: Flower Note: Standardized Extract, Valerian Root PlantPart: Root Note: Standardized extract, Chamomile Flower PlantPart: Flower Note: Standardized extract) | 25 mg | ||
| GABA | 10 mg | 96% of 744 products listing GABA give more (median 100 mg). | |
| Pyridoxal 5-Phosphate | 5 mg | 294%* | 51% of 15,277 products listing vitamin B6 give more (median 6 mg). |
| Melatonin | 3 mg | 38% of 1,557 products listing melatonin give more (median 3 mg). |
* % Daily Value computed from the printed amount and the FDA Daily Value (21 CFR 101.9); the label prints none for that row.
Source: NIH ODS Dietary Supplement Label Database, label 13399 (entered October 1, 2012), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.
Is that a lot?
The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:
- 96% of the 744 products that print an amount of GABA list more than its 10 mg of GABA (median 100 mg).
The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.
The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.
Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.
Which products have the closest formulas?
The products whose ingredient lists overlap most with Sleep-Assure With Botanical Extracts & Essential Cofactors's, rare ingredients counting for more.
- Melatonin Spray W/Bioavailability Enhancing Cofactors Natural PeppermintNature's Plus · off the market 3 shared, 83% alike
- Melatonin Activated Micro-Soluble Spray W/Bioavailability Enhancing Cofactors Natural PeppermintNatures Plus · off the market 3 shared, 83% alike
- Advanced Therapeutics Extended Delivery Serotain Rx-SleepNature's Plus · off the market 2 shared, 82% alike
- Sleep Assure Liquid Natural Lemon FlavorNature's Plus · off the market 3 shared, 75% alike
- Sleep Support with MelatoninNHC Natural Healthy Concepts 3 shared, 64% alike
- Bedtime PeppermintEssential Mints · off the market 2 shared, 61% alike
Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.
What does the label say about taking it?
Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.
- Directions
- DIRECTIONS: As a dietary supplement, one tablet 30 minutes before retiring.
- Warnings
- NOTICE: For adult use only.
- Melatonin should not be used except with a physician’s advice in the following conditions— pregnancy, lactation, serious illness, autoimmune disorders, diabetes, depression, endocrine disorders or during use of antidepressants or other prescription medications.
- Do not drive or operate heavy machinery while using.
- KEEP OUT OF REACH OF CHILDREN.
- Allergens and what it does not contain
- Free from artificial colors and preservatives. Free from the common allergens yeast, wheat, soy and milk.
- Storage
- KEEP TIGHTLY CLOSED IN A COOL, DRY PLACE.
Source: label statements in DSLD label 13399.
What else is on the label?
Other ingredients: Di-Calcium Phosphate, Microcrystalline Cellulose, Stearic Acid, Hydroxypropyl Methylcellulose, Magnesium Stearate, Silica, Pharmaceutical Glaze.
Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): GLUTEN Free; g MELA PURE(TM).
How many labels does Sleep-Assure With Botanical Extracts & Essential Cofactors have?
One label is on file, entered on October 1, 2012.
- Label 13399 (current) Entered October 1, 2012 · off the market July 31, 2015 · 60 bilayer tablets · UPC 0 97467 04760 0
DSLD also links this label to: Perfect Food Raw (image difference, same product), Perfect Food Raw (image difference, same product), Sleep-Assure (image difference, same product), Sleep-Assure (image difference, same product), Sleep-Assure (image difference, same product).
Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).
Who makes it?
The label names Natural Organics Laboratories, Inc. makers of Nature's Plus (manufacturer), Amityville, New York. All Nature's Plus products.