PlainVitamins

SIBOZyme

by Priority One Nutritional Supplements · capsule · 180 capsules

  • On the market (NIH)
  • UPC 8 15354 02172 0
  • DSLD label 310784
  • Serving 3 vegetarian capsules
  • 60 servings

SIBOZyme by Priority One Nutritional Supplements lists 11 ingredients, 8 with an amount per serving of 3 vegetarian capsules, such as 220 mg of betaine hydrochloride, 220 mg of L-glutamic acid, 300 mg of ox bile and 60 mg of amylase; 3 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on July 25, 2024.

What is in SIBOZyme?

Each row as the label prints it, per serving of 3 vegetarian capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

SIBOZyme: Supplement Facts rows against the market (DSLD label 310784, January 2026 release)
IngredientAmount% DVAmong products listing it
Betaine Hydrochloride98%220 mgBetaine Hydrochloride in SIBOZyme against 914 products220 mg per serving; the middle half of products list 25 mg to 178 mg, the median 50 mg.220 mg

Higher than 80% of 914 products listing betaine hydrochloride (median 50 mg). Per day at the most servings: 440 mg.

L-Glutamic Acid220 mgGlutamic Acid in SIBOZyme against 697 products220 mg per serving; the middle half of products list 25 mg to 364 mg, the median 80 mg.220 mg

Higher than 69% of 697 products listing glutamic acid (median 80 mg). Per day at the most servings: 440 mg.

Pancreatin8x400 mg
Amylase80,000 USPin the blend, no amount given
Lipase13,200 USPin the blend, no amount given
Protease80,000 USPin the blend, no amount given
Ox Bile300 mg
Amylase5,000 SKB/g60 mgAmylase in SIBOZyme against 326 products60 mg per serving; the middle half of products list 5 mg to 50 mg, the median 14 mg.60 mg

Higher than 81% of 326 products listing amylase (median 14 mg). Per day at the most servings: 120 mg.

Lactase50,000 ALU/g100 mgLactase in SIBOZyme against 138 products100 mg per serving; the middle half of products list 10 mg to 197.5 mg, the median 34 mg.100 mg

Higher than 69% of 138 products listing lactase (median 34 mg). Per day at the most servings: 200 mg.

Maltase10,000 DP/g100 mg
Sucrase10,000 Su/g100 mg
Prolyl Endopeptidaseas Aspergillus niger25 mg

Source: NIH ODS Dietary Supplement Label Database, label 310784 (entered July 25, 2024), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient; 3 ingredients sit inside a blend, so their amounts cannot be compared.

The NIH database records 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with SIBOZyme's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommendations: Take three (3) capsules two times daily before meals or as directed by your physician.
Warnings
Warning: If you are pregnant or breast feeding, consult your physician before using this product.
Keep out of reach of children.
For professional use only
Allergens and what it does not contain
Contains no preservatives. Bisphenol-A (BPA) & Phthalate free
Non-GMO
Storage
Keep container tightly closed, store in a cool, dry place.

Source: label statements in DSLD label 310784.

What else is on the label?

Other ingredients: Rice Flour, Hypromellose, Water, Purified.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): GMP Certified.

How many labels does SIBOZyme have?

5 labels are on file under this name since October 23, 2020: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 310784 (current) Entered July 25, 2024 · on the market · 180 capsules · UPC 8 15354 02172 0
  2. Label 310783 Entered July 25, 2024 · on the market · 180 capsules · UPC 8 15354 02030 3
  3. Label 255623 Entered September 24, 2021 · off the market March 30, 2023 · 180 capsules · UPC 8 15354 02172 0
  4. Label 236886 Entered November 21, 2020 · off the market March 30, 2023 · 180 capsules · UPC 8 15354 02030 3
  5. Label 236885 Entered October 23, 2020 · off the market June 15, 2021 · 180 capsules · UPC 8 15354 02172 0

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Priority One Nutritional Supplements, Inc. (distributor). All Priority One Nutritional Supplements products.

Where next?