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Life Extension · Non-Nutrient/Non-Botanical supplement

SAMe 200 mg S-Adenosyl-Methionine

13 ingredients on file in the NIH Dietary Supplement Label Database. Currently on-market in the U.S.

13
Ingredients
5
Nutrient categories
Top 32%
By ingredient count

SAMe 200 mg S-Adenosyl-Methionine is a non-nutrient/non-botanical supplement by Life Extension in tablet or pill form, listing 13 ingredients in the NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. Currently listed as on-market. Daily Value percentages shown below are based on FDA reference daily intake amounts for adults.

Product Details

Form
Tablet or Pill
Database Entry Date
2025-06-25
Ingredients
13

Supplement Facts (13 Ingredients)

Ingredient Group Amount % DV
S-Adenosyl Methionine SAMe Not disclosed on label No DV
Cellulose Cellulose Not disclosed on label No DV
Mannitol Mannitol Not disclosed on label No DV
Methacrylic Acid Copolymer Polyacrylate Not disclosed on label No DV
Citric Acid Citric Acid Not disclosed on label No DV
Stearic Acid Stearic Acid Not disclosed on label No DV
Silica Silicon Not disclosed on label No DV
Calcium Carbonate Calcium Not disclosed on label No DV
Hypromellose Hypromellose Not disclosed on label No DV
Glyceryl Triacetate Triacetin Not disclosed on label No DV
Sodium Starch Glycolate Sodium Starch Glycolate Not disclosed on label No DV
Croscarmellose Sodium Croscarmellose Not disclosed on label No DV
yellow Ochre Color Not disclosed on label No DV

How does SAMe 200 mg S-Adenosyl-Methionine compare?

Ingredients listed on each label, against the non-nutrient/non-botanical category average of 6.9. Data from the NIH DSLD.

SAMe 200 mg S-Adenosyl-Methionine13
1 Andro Stenelone9
Non-Nutrient/Non-Botanical average6.9

SAMe 200 mg S-Adenosyl-Methionine lists 4 ingredients more than 1 Andro Stenelone. That is 6 above the non-nutrient/non-botanical average.

What the Label Data Shows

SAMe 200 mg S-Adenosyl-Methionine is cataloged in the NIH Dietary Supplement Label Database (DSLD) as a non-nutrient/non-botanical supplement built from 13 ingredients from Life Extension, sold in tablet or pill form. These ingredients span 5 nutrient categories, other, non-nutrient/non-botanical, mineral, fiber, and 1 more, reflecting a multi-component formula rather than a single-nutrient product.

Across a broader 13-ingredient formula, 13 of 13 fall outside the FDA's Daily Value system altogether, expected for a broader formula -- the more ingredients a label lists, the more likely it accumulates botanicals, amino acids, or specialty compounds the FDA has never benchmarked.

Market status matters for supplement research. This product is currently listed as on-market in the DSLD, with its label first entered into the database on 2025-06-25. An on-market listing means the product is currently sold in the United States; the DSLD catalogs the label as submitted but does not independently verify the claims or evaluate safety or efficacy.

About the DSLD database

The DSLD is a label database, not an FDA approval list, under the 1994 DSHEA framework, dietary supplements do not require pre-market approval, and label information reflects what manufacturers self-declare rather than independent laboratory verification. This page presents factual label data for reference only and is not medical advice; consult a licensed healthcare provider before making decisions about any supplement.

Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD) Supplement label data for SAMe 200 mg S-Adenosyl-Methionine: ingredients, % Daily Value, market status, brand · 2026 DSLD captures manufacturer-self-declared label information; the NIH does not verify accuracy or evaluate safety/efficacy. Dietary supplements are regulated under DSHEA 1994, no pre-market FDA approval is required.

Ingredient Breakdown by Category

other
5
Methacrylic Acid Copolymer, Hypromellose, Sodium Starch Glycolate, +2 more
non-nutrient/non-botanical
4
S-Adenosyl Methionine, Mannitol, Citric Acid, +1 more
mineral
2
Silica, Calcium Carbonate
fiber
1
Cellulose
fatty acid
1
Stearic Acid

Daily Value Coverage

0
Above 100% DV
0
Below 100% DV
13
No DV Established

Frequently Asked Questions

What ingredients are in SAMe 200 mg S-Adenosyl-Methionine?
SAMe 200 mg S-Adenosyl-Methionine contains 13 ingredients. Ingredients span 5 categories: other, non-nutrient/non-botanical, mineral, fiber, fatty acid.
Who manufactures SAMe 200 mg S-Adenosyl-Methionine?
SAMe 200 mg S-Adenosyl-Methionine is currently manufactured by Life Extension. It is classified as a Non-Nutrient/Non-Botanical supplement in tablet or pill form.
Is SAMe 200 mg S-Adenosyl-Methionine still available for purchase?
Yes, SAMe 200 mg S-Adenosyl-Methionine is currently listed as on-market in the NIH DSLD database.
What is the serving size of SAMe 200 mg S-Adenosyl-Methionine?
The serving size is not specified.
What type of supplement is SAMe 200 mg S-Adenosyl-Methionine?
SAMe 200 mg S-Adenosyl-Methionine is classified as a "Non-Nutrient/Non-Botanical" supplement in the NIH database. This category includes products primarily composed of non-nutrient/non-botanical ingredients. Across the full DSLD catalog, products fall into 9 possible categories: Vitamin, Mineral, Botanical, Amino Acid & Protein, Non-Nutrient, Fat & Fatty Acid, Multi-Vitamin & Mineral, Botanical with Nutrients, and Other Combinations.
Data Sources & Methodology

Data as of 2025. Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD).

Supplement label data sourced from the Source: NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. The DSLD contains label information from dietary supplement products marketed in the United States.

Daily Value (DV) percentages are based on Source: FDA 21 CFR 101.9 Reference Daily Intake (RDI) values for adults. Products marked "Off Market" may no longer be available for purchase but their label data remains in the database for reference.

Disclaimer, Not Medical Advice

Label data from the Source: NIH Dietary Supplement Label Database (DSLD). This information is for educational and reference purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting, stopping, or combining any dietary supplement, especially if you are pregnant, nursing, take prescription medication, or have a medical condition.

Every figure on PlainVitamins is rendered directly from the NIH Dietary Supplement Label Database (DSLD), no number is typed in by an editor. This page draws directly on the NIH DSLD, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.