PlainVitamins

SAM-e Joint

by Jarrow Formulas · tablet or pill · 60 tablets

  • Off the market since February 2019 (NIH)
  • UPC 7 90011 20019 2
  • DSLD label 37701
  • Serving 1 tablet
  • 60 servings

SAM-e Joint by Jarrow Formulas lists 3 ingredients, 3 with an amount per serving of 1 tablet, such as 525 mg of glucosamine HCl and 200 mg of S-adenosyl methionine. Its current label entered the NIH Dietary Supplement Label Database on October 10, 2014.

What is in SAM-e Joint?

Each row as the label prints it, per serving of 1 tablet. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

SAM-e Joint: Supplement Facts rows against the market (DSLD label 37701, January 2026 release)
IngredientAmount% DVAmong products listing it
Glucosamine HCl525 mgGlucosamine Hydrochloride in SAM-e Joint against 628 products0.525 g per serving; the middle half of products list 0.75 g to 1.5 g, the median 1.5 g.0.525 g

79% of 628 products listing glucosamine hydrochloride give more (median 1.5 g). Per day at the most servings: 1.05 g.

S-Adenosyl Methionine200 mgSAMe in SAM-e Joint against 163 products200 mg per serving; the middle half of products list 200 mg to 400 mg, the median 200 mg.200 mg

48% of 163 products listing SAMe give more (median 200 mg). Per day at the most servings: 400 mg.

from 400 mg of SAM-e Tosylate Disulfate400 mg

Source: NIH ODS Dietary Supplement Label Database, label 37701 (entered October 10, 2014), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records 1 to 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

1 product lists the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
USAGE: Take 1 tablet 1 or 2 times per day on an empty stomach or as directed by your qualified healthcare professional.
For best results, use with Jarrow Formulas(R) JarroSil(R), the biologically Activated Silicon(R).
Warnings
WARNING: Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using.
Individuals with Parkinson’s disease, bipolar disorder or manic depression should not use SAM-e.
DO NOT use if seal of blister pack is broken.
Keep out of the reach of children.
Do not use if pregnant or nursing.
Do not exceed recommended intake. May cause gastrointestinal upset in some persons. If you experience discomfort, discontinue use.
Allergens and what it does not contain
No wheat, no gluten, no soybeans, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts.
Jarrow Formulas(R) SAM-e Joint(R) is Joint Sustain(R) nutrition, providing glucosamine HCI, a SODIUM FREE form of glucosamine.
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 37701.

What else is on the label?

Other ingredients: Cellulose, Glyceryl Behenate, Medium Chain Triglycerides, Oleic Acid, Sodium Alginate, Titanium Dioxide, Riboflavin, Stearic Acid, Silicon Dioxide, Magnesium Stearate, Dextrin, Dextrose, Sodium Citrate.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): v vegan.

How many labels does SAM-e Joint have?

3 labels are on file under this name since April 26, 2012: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 37701 (current) Entered October 10, 2014 · off the market February 13, 2019 · 60 tablets · UPC 7 90011 20019 2
  2. Label 29985 Entered February 26, 2014 · off the market September 4, 2014 · 60 tablets · UPC 7 90011 20019 2
  3. Label 7705 Entered April 26, 2012 · off the market December 13, 2013 · 60 enteric coated tablets · UPC 7 90011 20019 2

DSLD also links this label to: SAMe Joint (image difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Jarrow Formulas Superior Nutrition and Formulation (distributor), Los Angeles, CA. All Jarrow Formulas products.

Where next?