PhysioLogics · Other Combinations supplement
SAM-e 400 mg Double Strength
15 ingredients on file in the NIH Dietary Supplement Label Database. Off-market, label data preserved for reference.
- 15
- Ingredients
- 7
- Nutrient categories
- Top 26%
- By ingredient count
SAM-e 400 mg Double Strength is a other combinations supplement by PhysioLogics in tablet or pill form, listing 15 ingredients in the NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. Currently listed as off-market (no longer available for purchase, but label data is preserved). Daily Value percentages shown below are based on FDA reference daily intake amounts for adults.
Product Details
- Type
- 🔬 Other Combinations
- Form
- Tablet or Pill
- Database Entry Date
- 2011-12-23
- Ingredients
- 15
Supplement Facts (15 Ingredients)
| Ingredient | Group | Amount | % DV |
|---|---|---|---|
| Vitamin C | Vitamin C | Not disclosed on label | No DV |
| Riboflavin | Riboflavin | Not disclosed on label | No DV |
| S-Adenosylmethionine | SAMe | Not disclosed on label | No DV |
| Cellulose | Cellulose | Not disclosed on label | No DV |
| Polymethacrylate | Polyacrylate | Not disclosed on label | No DV |
| Citric Acid | Citric Acid | Not disclosed on label | No DV |
| Croscarmellose | Croscarmellose | Not disclosed on label | No DV |
| Triethyl Citrate | triethylcitrate | Not disclosed on label | No DV |
| Silica | Silicon | Not disclosed on label | No DV |
| Titanium Dioxide color | Titanium Dioxide | Not disclosed on label | No DV |
| Vegetable Magnesium Stearate | Magnesium stearate | Not disclosed on label | No DV |
| Mannitol | Mannitol | Not disclosed on label | No DV |
| Glycerol Palmitostearate | Glyceryl palmitostearate | Not disclosed on label | No DV |
| Stearic Acid | Stearic Acid | Not disclosed on label | No DV |
| Medium Chain Triglycerides | Medium chain triglycerides (MCT) | Not disclosed on label | No DV |
How does SAM-e 400 mg Double Strength compare?
Ingredients listed on each label, against the other combinations category average of 21.8. Data from the NIH DSLD.
SAM-e 400 mg Double Strength lists 19 ingredients fewer than 1,000 mg Vitamin C Acai Berry. That is 7 below the other combinations average.
What the Label Data Shows
SAM-e 400 mg Double Strength is cataloged in the NIH Dietary Supplement Label Database (DSLD) as a other combinations supplement built from 15 ingredients from PhysioLogics, sold in tablet or pill form. These ingredients span 7 nutrient categories, other, non-nutrient/non-botanical, vitamin, fiber, and 3 more, reflecting a multi-component formula rather than a single-nutrient product.
Across a broader 15-ingredient formula, 15 of 15 carry no FDA reference-intake value, typical for a formula this size: larger blends tend to pull in botanicals, amino acids, and specialty compounds without an assigned Daily Value. Breadth like this isn't a red flag by itself.
Market status matters for supplement research. This product is currently listed as off-market in the DSLD, with its label first entered into the database on 2011-12-23. Once a product goes off-market, it is no longer manufactured or sold under this label, yet the DSLD keeps the record intact for historical reference, useful for researchers, anyone with an older bottle on hand, or tracking how formulations changed over time.
About the DSLD database
The DSLD is a label database, not an FDA approval list, under the 1994 DSHEA framework, dietary supplements do not require pre-market approval, and label information reflects what manufacturers self-declare rather than independent laboratory verification. This page presents factual label data for reference only and is not medical advice; consult a licensed healthcare provider before making decisions about any supplement.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD) Supplement label data for SAM-e 400 mg Double Strength: ingredients, % Daily Value, market status, brand · 2026 DSLD captures manufacturer-self-declared label information; the NIH does not verify accuracy or evaluate safety/efficacy. Dietary supplements are regulated under DSHEA 1994, no pre-market FDA approval is required.
Ingredient Breakdown by Category
Daily Value Coverage
Frequently Asked Questions
What ingredients are in SAM-e 400 mg Double Strength? ▼
Who manufactures SAM-e 400 mg Double Strength? ▼
Is SAM-e 400 mg Double Strength still available for purchase? ▼
What is the serving size of SAM-e 400 mg Double Strength? ▼
What type of supplement is SAM-e 400 mg Double Strength? ▼
Data Sources & Methodology
Data as of 2025. Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD).
Supplement label data sourced from the Source: NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. The DSLD contains label information from dietary supplement products marketed in the United States.
Daily Value (DV) percentages are based on Source: FDA 21 CFR 101.9 Reference Daily Intake (RDI) values for adults. Products marked "Off Market" may no longer be available for purchase but their label data remains in the database for reference.
Disclaimer, Not Medical Advice
Label data from the Source: NIH Dietary Supplement Label Database (DSLD). This information is for educational and reference purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting, stopping, or combining any dietary supplement, especially if you are pregnant, nursing, take prescription medication, or have a medical condition.
Read our methodology , how this data is sourced, computed, and verified.
Every figure on PlainVitamins is rendered directly from the NIH Dietary Supplement Label Database (DSLD), no number is typed in by an editor. This page draws directly on the NIH DSLD, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.