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PhysioLogics · Other Combinations supplement

SAM-e 400 mg Double Strength

15 ingredients on file in the NIH Dietary Supplement Label Database. Off-market, label data preserved for reference.

15
Ingredients
7
Nutrient categories
Top 26%
By ingredient count

SAM-e 400 mg Double Strength is a other combinations supplement by PhysioLogics in tablet or pill form, listing 15 ingredients in the NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. Currently listed as off-market (no longer available for purchase, but label data is preserved). Daily Value percentages shown below are based on FDA reference daily intake amounts for adults.

Product Details

Form
Tablet or Pill
Database Entry Date
2011-12-23
Ingredients
15

Supplement Facts (15 Ingredients)

Per-row amounts not disclosed: The NIH DSLD record for this product lists ingredients but does not include the per-row Supplement Facts panel (quantities and Daily Value percentages). The full panel may be visible on the physical label or on the manufacturer's site. Verify amounts before use. Look up on NIH DSLD →
Ingredient Group Amount % DV
Vitamin C Vitamin C Not disclosed on label No DV
Riboflavin Riboflavin Not disclosed on label No DV
S-Adenosylmethionine SAMe Not disclosed on label No DV
Cellulose Cellulose Not disclosed on label No DV
Polymethacrylate Polyacrylate Not disclosed on label No DV
Citric Acid Citric Acid Not disclosed on label No DV
Croscarmellose Croscarmellose Not disclosed on label No DV
Triethyl Citrate triethylcitrate Not disclosed on label No DV
Silica Silicon Not disclosed on label No DV
Titanium Dioxide color Titanium Dioxide Not disclosed on label No DV
Vegetable Magnesium Stearate Magnesium stearate Not disclosed on label No DV
Mannitol Mannitol Not disclosed on label No DV
Glycerol Palmitostearate Glyceryl palmitostearate Not disclosed on label No DV
Stearic Acid Stearic Acid Not disclosed on label No DV
Medium Chain Triglycerides Medium chain triglycerides (MCT) Not disclosed on label No DV

How does SAM-e 400 mg Double Strength compare?

Ingredients listed on each label, against the other combinations category average of 21.8. Data from the NIH DSLD.

SAM-e 400 mg Double Strength15
1,000 mg Vitamin C Acai Berry34
Other Combinations average21.8

SAM-e 400 mg Double Strength lists 19 ingredients fewer than 1,000 mg Vitamin C Acai Berry. That is 7 below the other combinations average.

What the Label Data Shows

SAM-e 400 mg Double Strength is cataloged in the NIH Dietary Supplement Label Database (DSLD) as a other combinations supplement from PhysioLogics, sold in tablet or pill form. The label declares 15 ingredients. These ingredients span 7 nutrient categories, other, non-nutrient/non-botanical, vitamin, fiber, and 3 more, reflecting a multi-component formula rather than a single-nutrient product.

Daily Value coverage on this label is informative. No ingredients on this label reach 100% of the FDA reference Daily Value, 0 fall below 100% DV, and 15 have no FDA-established Daily Value reference.. Some nutrients (such as botanicals, amino acids, and specialty compounds) have no Daily Value because the FDA has not set a reference intake; absence of a DV is neither good nor bad on its own.

Market status matters for supplement research. This product is currently listed as off-market in the DSLD, with its label first entered into the database on 2011-12-23. Off-market products are no longer being produced or distributed under this label, but the DSLD preserves their historical label data for researchers, consumers checking older bottles, and for tracking how formulations have evolved. The DSLD is a label database, not an FDA approval list, under the 1994 DSHEA framework, dietary supplements do not require pre-market approval, and label information reflects what manufacturers self-declare rather than independent laboratory verification. This page presents factual label data for reference only and is not medical advice; consult a licensed healthcare provider before making decisions about any supplement.

Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD) Supplement label data for SAM-e 400 mg Double Strength: ingredients, % Daily Value, market status, brand · 2026 DSLD captures manufacturer-self-declared label information; the NIH does not verify accuracy or evaluate safety/efficacy. Dietary supplements are regulated under DSHEA 1994, no pre-market FDA approval is required.

Nearby Other Combinations Products

Other products in the NIH DSLD cataloged under the same supplement type. Useful for comparing formulations within the other combinations category.

Compare SAM-e 400 mg Double Strength vs 1,000 mg Vitamin C Acai Berry →

Ingredient Breakdown by Category

other
6
Polymethacrylate, Croscarmellose, Triethyl Citrate, +3 more
non-nutrient/non-botanical
3
S-Adenosylmethionine, Citric Acid, Mannitol
vitamin
2
Vitamin C, Riboflavin
fiber
1
Cellulose
mineral
1
Silica
fatty acid
1
Stearic Acid
fat
1
Medium Chain Triglycerides

Daily Value Coverage

0
Above 100% DV
0
Below 100% DV
15
No DV Established

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Frequently Asked Questions

What ingredients are in SAM-e 400 mg Double Strength?
SAM-e 400 mg Double Strength contains 15 ingredients. Ingredients span 7 categories: other, non-nutrient/non-botanical, vitamin, fiber, mineral, fatty acid, fat.
Who manufactures SAM-e 400 mg Double Strength?
SAM-e 400 mg Double Strength is was manufactured by PhysioLogics. It is classified as a Other Combinations supplement in tablet or pill form.
Is SAM-e 400 mg Double Strength still available for purchase?
According to the NIH DSLD database, SAM-e 400 mg Double Strength is listed as off-market and may no longer be available for purchase.
What is the serving size of SAM-e 400 mg Double Strength?
The serving size is not specified.
What type of supplement is SAM-e 400 mg Double Strength?
SAM-e 400 mg Double Strength is classified as a "Other Combinations" supplement in the NIH database. This category includes products primarily composed of other combinations ingredients. The NIH DSLD tracks 9 supplement categories: Vitamin, Mineral, Botanical, Amino Acid & Protein, Non-Nutrient, Fat & Fatty Acid, Multi-Vitamin & Mineral, Botanical with Nutrients, and Other Combinations.
Where does this SAM-e 400 mg Double Strength data come from?
All label data comes from the NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. The DSLD is a publicly accessible database containing label information, including ingredients, serving sizes, and Daily Value percentages, for dietary supplement products marketed in the United States.

Data Sources & Methodology

Data as of 2025. Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD).

Supplement label data sourced from the Source: NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. The DSLD contains label information from dietary supplement products marketed in the United States.

Daily Value (DV) percentages are based on Source: FDA 21 CFR 101.9 Reference Daily Intake (RDI) values for adults. Products marked "Off Market" may no longer be available for purchase but their label data remains in the database for reference.

Disclaimer, Not Medical Advice: Label data from the Source: NIH Dietary Supplement Label Database (DSLD). This information is for educational and reference purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting, stopping, or combining any dietary supplement, especially if you are pregnant, nursing, take prescription medication, or have a medical condition.