PlainVitamins

SAM-e

by GNC TriFlex · capsule · 90 capsules

  • On the market (NIH)
  • UPC 0 48107 06914 8
  • DSLD label 3203
  • Serving 3 capsules
  • 30 servings

SAM-e by GNC TriFlex lists 4 ingredients, 4 with an amount per serving of 3 capsules, such as 1,500 mg of glucosamine sulfate, 1,200 mg of chondroitin sulfate sodium, 500 mg of MSM and 100 mg of SAM-e, beside 2 Nutrition Facts rows (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on December 23, 2011.

What is in SAM-e?

Each row as the label prints it, per serving of 3 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

SAM-e: Supplement Facts rows against the market (DSLD label 3203, January 2026 release)
IngredientAmount% DVAmong products listing it
Calories5 Calories
Total Carbohydrates1 g1%Carbohydrate in SAM-e against 21,979 products1 g per serving; the middle half of products list 1 g to 6 g, the median 3 g.1 g

74% of 21,979 products listing carbohydrate give more (median 3 g).

Sodium120 mg5%Sodium in SAM-e against 14,514 products120 mg per serving; the middle half of products list 15 mg to 142 mg, the median 55 mg.120 mg

Higher than 69% of 14,514 products listing sodium (median 55 mg).

Glucosamine Sulfateas Glucosamine Sulfate 2KCl1,500 mgGlucosamine Sulfate in SAM-e against 875 products1.5 g per serving; the middle half of products list 0.5 g to 1.5 g, the median 1 g.1.5 g

Higher than 64% of 875 products listing glucosamine sulfate (median 1 g).

Chondroitin Sulfate Sodium1,200 mgChondroitin Sulfate in SAM-e against 950 products1,200 mg per serving; the middle half of products list 200 mg to 1,200 mg, the median 400 mg.1,200 mg

Higher than 74% of 950 products listing chondroitin sulfate (median 400 mg).

MSM500 mgMethylsulfonylmethane in SAM-e against 1,454 products500 mg per serving; the middle half of products list 150 mg to 1,000 mg, the median 500 mg.500 mg

36% of 1,454 products listing methylsulfonylmethane give more (median 500 mg).

SAM-e100 mgSAMe in SAM-e against 163 products100 mg per serving; the middle half of products list 200 mg to 400 mg, the median 200 mg.100 mg

82% of 163 products listing SAMe give more (median 200 mg).

Source: NIH ODS Dietary Supplement Label Database, label 3203 (entered December 23, 2011), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with SAM-e's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: As a dietary supplement, take three capsules daily.
Warnings
Contains: Shellfish (shrimp).
Warning: Do not use if pregnant or nursing.
Do not exceed recommended dose.
If you are taking any medication or are under the care of a physician for depression or related disorder, contact your physician before using this product.
May cause gastrointestinal upset in some persons. If you experience discomfort, discontinue use.
Keep out of reach of children
Allergens and what it does not contain
No artificial colors, no artificial flavors, no wheat, no gluten, no yeast, no lactose, no milk or milk derivatives, no sugar.
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 3203.

What else is on the label?

Other ingredients: Gelatin, Silica, Vegetable Magnesium Stearate.

How many labels does SAM-e have?

One label is on file, entered on December 23, 2011.

  1. Label 3203 (current) Entered December 23, 2011 · on the market · 90 capsules · UPC 0 48107 06914 8

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names General Nutrition Corporation (distributor), Pittsburgh, PA. All GNC TriFlex products.

Where next?