Rest & Renew

by Life Extension · capsule · 30 vegetarian capsules

  • On the market (NIH)
  • UPC 7 37870 25023 4
  • DSLD label 328650
  • Serving 1 vegetarian capsule
  • 30 servings

Rest & Renew by Life Extension lists 2 ingredients, 2 with an amount per serving of 1 vegetarian capsule, such as 120 mg of shoden and 1.5 mg of melatonin. Its current label entered the NIH Dietary Supplement Label Database on June 25, 2025.

What is in Rest & Renew?

Each row as the label prints it, per serving of 1 vegetarian capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Rest & Renew: Supplement Facts rows against the market (DSLD label 328650, January 2026 release)
IngredientAmount% DVAmong products listing it
Shodenas Ashwagandha Leaf Extract, Ashwagandha Root Extractstd. to 35% withanolide glycosides120 mgAshwagandha in Rest & Renew against 1,646 products120 mg per serving; the middle half of products list 125 mg to 500 mg, the median 250 mg.120 mg

76% of 1,646 products listing ashwagandha give more (median 250 mg).

Melatonin1.5 mgMelatonin in Rest & Renew against 1,557 products1.5 mg per serving; the middle half of products list 2 mg to 5 mg, the median 3 mg.1.5 mg

77% of 1,557 products listing melatonin give more (median 3 mg).

Source: NIH ODS Dietary Supplement Label Database, label 328650 (entered June 25, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Rest & Renew's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: Take one (1) capsule 30 to 60 minutes before bedtime, or as recommended by a healthcare practitioner.
Warnings
Read the entire label and follow the directions carefully prior to use. Caution: Do not consume alcohol, drive or operate heavy machinery after taking this product.
Warnings: Keep out of reach of children.
Do not exceed recommended dose. Do not purchase if outer seal is damaged.
Consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
To report a serious adverse event or obtain product information, contact 1-866-280-2852.
Allergens and what it does not contain
Gluten free Non GMO LE certified
Storage
Store tightly closed in a cool, dry place.

Source: label statements in DSLD label 328650.

What else is on the label?

Other ingredients: Microcrystalline Cellulose, Cellulose, Dicalcium Phosphate, Stearate, Sodium Alginate, Silica, Carnauba Wax.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Non GMO LE certified.

How many labels does Rest & Renew have?

One label is on file, entered on June 25, 2025.

  1. Label 328650 (current) Entered June 25, 2025 · on the market · 30 vegetarian capsules · UPC 7 37870 25023 4

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Quality Supplements and Vitamins, Inc. (distributor), Ft. Lauderdale, FL. All Life Extension products.

Where next?