PlainVitamins

Protrypsin

by Metagenics · tablet or pill · 60 tablets

  • On the market (NIH)
  • UPC 7 55571 91036 3
  • DSLD label 216280
  • Serving 2 tablets
  • 30 servings

Protrypsin by Metagenics lists 4 ingredients, 2 with an amount per serving of 2 tablets, such as 100 mg of raw pancreas concentrate and 133 mg of bromelain; 2 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on March 24, 2020.

What is in Protrypsin?

Each row as the label prints it, per serving of 2 tablets. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Protrypsin: Supplement Facts rows against the market (DSLD label 216280, January 2026 release)
IngredientAmount% DVAmong products listing it
ChymotrypsinChymotrypsin Note: not less than 6,000 USP unitsno amount given
TrypsinTrypsin Note: not less than 6,000 USP unitsno amount given
Raw Pancreas Concentrateas Porcine100 mgPancreas in Protrypsin against 93 products100 mg per serving; the middle half of products list 32 mg to 350 mg, the median 100 mg.100 mg

49% of 93 products listing pancreas give more (median 100 mg). Per day at the most servings: 300 mg.

BromelainBromelain Note: 2,400 GDU/g133 mgBromelain in Protrypsin against 1,337 products133 mg per serving; the middle half of products list 25 mg to 200 mg, the median 50 mg.133 mg

Higher than 67% of 1,337 products listing bromelain (median 50 mg). Per day at the most servings: 399 mg.

Source: NIH ODS Dietary Supplement Label Database, label 216280 (entered March 24, 2020), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient; 2 ingredients sit inside a blend, so their amounts cannot be compared.

The NIH database records 1 to 3 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Protrypsin's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: Take two tablets one to three times daily between meals or as directed by your healthcare practitioner.
Warnings
Caution: If pregnant or nursing, consult your healthcare practitioner before use if taking other nutritional supplements or medications.
Do not use if there is a prior history of or a current peptic or duodenal ulcer.
Keep out of the reach of children.
Do not use in individuals who have a known allergy or hypersensitivity to pork or pork protein.
Contains: Milk.
Allergens and what it does not contain
This product is non-GMO and gluten-free.
Storage
Storage: To help maintain potency after opening, keep this bottle tightly closed and store in a cool, dry place. Do not refrigerate. Refrigeration may cause moisture condensation on the product.

Source: label statements in DSLD label 216280.

What else is on the label?

Other ingredients: Microcrystalline Cellulose, Stearic Acid, Croscarmellose Sodium, Silica, Enteric Coating.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): GF Certified Gluten-free. Listed with: Certified gluten-free (GFCO) (a seal is the label's claim; the certifier's own list confirms it).

How many labels does Protrypsin have?

4 labels are on file under this name since November 25, 2013: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 216280 (current) Entered March 24, 2020 · on the market · 60 tablets · UPC 7 55571 91036 3
  2. Label 216279 Entered March 24, 2020 · on the market · 120 tablets · UPC 7 55571 91037 0
  3. Label 209713 Entered December 22, 2019 · off the market December 27, 2019 · 60 tablets
  4. Label 27705 Entered November 25, 2013 · off the market July 3, 2019 · 120 tablets · UPC 7 55571 91037 0

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Metagenics (manufacturer), Gig Harbor, WA. All Metagenics products.

Where next?