Pro-Resolving Mediators

by Life Extension · softgel capsule · 30 softgels

  • On the market (NIH)
  • UPC 7 37870 22233 0
  • DSLD label 328645
  • Serving 1 softgel
  • 30 servings

Pro-Resolving Mediators by Life Extension lists 4 ingredients, 1 with an amount per serving of 1 softgel, such as 500 mg of marine lipid concentrate; 3 sit inside a blend without their own amounts, beside 2 Nutrition Facts rows (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on May 21, 2025.

What is in Pro-Resolving Mediators?

Each row as the label prints it, per serving of 1 softgel. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Pro-Resolving Mediators: Supplement Facts rows against the market (DSLD label 328645, January 2026 release)
IngredientAmount% DVAmong products listing it
Calories5 Calories
Total Fat0.5 g1%Fat (unspecified) in Pro-Resolving Mediators against 11,965 products0.5 g per serving; the middle half of products list 1 g to 2.5 g, the median 1.5 g.0.5 g

86% of 11,965 products listing fat (unspecified) give more (median 1.5 g).

Cholesterolless than 5 mg2%
Marine Lipid Concentrate500 mgFish Oil in Pro-Resolving Mediators against 1,990 products0.5 g per serving; the middle half of products list 1 g to 2 g, the median 1.2 g.0.5 g

85% of 1,990 products listing fish oil give more (median 1.2 g).

Pro-resolving Mediatorsincluding300 mcg
18-Hydroxy-Eicosapentaenoic Acidin the blend, no amount given
17-Hydroxy-Docosahexaenoic Acidin the blend, no amount given
14-Hydroxy-Docosahexaenoic Acidin the blend, no amount given

Source: NIH ODS Dietary Supplement Label Database, label 328645 (entered May 21, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient; 3 ingredients sit inside a blend, so their amounts cannot be compared.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Pro-Resolving Mediators's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: Take one (1) softgel daily, or as recommended by a healthcare practitioner.
Warnings
Read the entire label and follow the directions carefully prior to use.
Warnings: Keep out of reach of children.
Do not exceed recommended dose. Do not purchase if outer seal is damaged.
Consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
To report a serious adverse event or obtain product information, contact 1-866-280-2852.
Allergens and what it does not contain
Gluten free Non GMO Le certified
Storage
Store tightly closed in a cool, dry place.

Source: label statements in DSLD label 328645.

What else is on the label?

Other ingredients: Highly Refined Marine Oil Concentrate, Gelatin, Olive Oil, Glycerin, Water, Purified, Lemon Flavor, Mixed Tocopherols.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Non GMO Le certified.

How many labels does Pro-Resolving Mediators have?

3 labels are on file under this name since August 23, 2020: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 328645 (current) Entered May 21, 2025 · on the market · 30 softgels · UPC 7 37870 22233 0
  2. Label 232739 Entered August 23, 2020 · off the market July 14, 2020 · 30 softgels · UPC 7 37870 22233 0
  3. Label 232369 Entered August 23, 2020 · off the market August 9, 2023 · 30 softgels · UPC 7 37870 22233 0

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Quality Supplements and Vitamins, Inc. (distributor), Ft. Lauderdale, FL. All Life Extension products.

Where next?