Pro-15

by Hyperbiotics · tablet or pill · 60 Patented, Time-Release Micro-Pearls

Off the market since February 2023 (NIH)
UPC 9 506000 058504
DSLD label 270127
Serving 1 to 3 pearl tablets; amounts per 1 pearl tablet
60 servings

Pro-15 by Hyperbiotics lists 16 ingredients, 1 with an amount per serving of 1 pearl tablet, such as 25 mg of fructooligosaccharides; 15 sit inside a blend without their own amounts, beside 3 Nutrition Facts rows (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on September 22, 2022.

What is in Pro-15?

Each row as the label prints it, per serving of 1 pearl tablet. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Pro-15: Supplement Facts rows against the market (DSLD label 270127, January 2026 release)
Ingredient	Amount	% DV	Among products listing it
Total Carbohydrates	0 g	1%
Total Sugars	0 g
Added Sugars	no amount given	1%
Proprietary Probiotic Blend	(5 billion CFU) (At the time of manufacture. Minimum 1.5 billion CFU at expiration)
Lactobacillus plantarum	in the blend, no amount given
Lactobacillus fermentum	in the blend, no amount given
Lactobacillus acidophilus	in the blend, no amount given
Bifidobacterium longum infantis	in the blend, no amount given
Lactobacillus casei casei	in the blend, no amount given
Bifidobacterium longum	in the blend, no amount given
Lactobacillus rhamnosus	in the blend, no amount given
Bifidobacterium animalis lactis	in the blend, no amount given
Lactobacillus reuteri	in the blend, no amount given
Lactobacillus salivarius	in the blend, no amount given
Lactobacillus paracasei	in the blend, no amount given
Lactobacillus gasseri	in the blend, no amount given
Bifidobacterium bifidum	in the blend, no amount given
Bifidobacterium breve	in the blend, no amount given
Streptococcus thermophilus	in the blend, no amount given
Fructooligosaccharidesprebiotic fructooligosaccharides (FOS)	25 mg		88% of 526 products listing fructo-oligosaccharides give more (median 185 mg).

Source: NIH ODS Dietary Supplement Label Database, label 270127 (entered September 22, 2022), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

88% of the 526 products that print an amount of fructo-oligosaccharides list more than its 25 mg of fructooligosaccharides (filed by NIH under fructo-oligosaccharides) (median 185 mg).

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

1 product lists the very same ingredients; the nearest amounts come first.

PRO-15 Prebiotic+ProbioticHyperbiotics same ingredients
Probiotic 5 BillionSEROLife 16 shared, 95% alike
PRO-15 Advanced StrengthHyperbiotics · off the market 17 shared, 85% alike
PRO-15 Advanced UnflavoredHyperbiotics 17 shared, 85% alike
Advanced Probiotic ComplexThrive Naturals 15 shared, 79% alike
Probiotic-16Purity Labs · off the market 15 shared, 78% alike

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions: When taken regularly as part of a balanced diet and healthy lifestyle.; Daily Maintenance: Take 1 pearl tablet once per day. Intense Support: Take up to 3 pearl tablets per day.
Warnings: Note: Consult your healthcare professional. Do not use if seal is broken or missing.; Keep out of reach of children.
Allergens and what it does not contain: Dairy free Gluten free; This formula is dairy free.; Vegetarian; non-GMO; yeast free; no dairy, no soy, no gluten, no wheat, no nuts, no preservatives, no sugar, no artificial colors or flavors.
Storage: No Refrigeration Necessary: Store in a cool, dry place.

Source: label statements in DSLD label 270127.

What else is on the label?

Other ingredients: Microcrystalline Cellulose, Hydroxypropylmethylcellulose, Pectin, Stearic Acid, Sodium Carbonate, Guar Gum, Turmeric.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Made in the USA.

How many labels does Pro-15 have?

2 labels are on file under this name since October 25, 2018: other sizes, label designs and reformulations. The current one leads this page.

Label 270127 (current) Entered September 22, 2022 · off the market February 17, 2023 · 60 Patented, Time-Release Micro-Pearls · UPC 9 506000 058504
Label 182275 Entered October 25, 2018 · off the market November 23, 2021 · 60 Patented, Time-Release Micro-Pearls · UPC 9 506000 058504

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Hyperbiotics (distributor), Henderson, NV. All Hyperbiotics products.