Pregnenolone

by Core Nutritionals · capsule · 90 vegetable caps

  • On the market (NIH)
  • UPC 6 72975 31543 6
  • DSLD label 298259
  • Serving 1 capsule
  • 90 servings

Pregnenolone by Core Nutritionals lists one ingredient: 25 mg of pregnenolone per serving of 1 capsule. Its current label entered the NIH Dietary Supplement Label Database on October 24, 2023.

What is in Pregnenolone?

Each row as the label prints it, per serving of 1 capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Pregnenolone: Supplement Facts rows against the market (DSLD label 298259, January 2026 release)
IngredientAmount% DVAmong products listing it
Pregnenolone25 mgPregnenolone in Pregnenolone against 142 products25 mg per serving; the middle half of products list 10 mg to 50 mg, the median 25 mg.25 mg

44% of 142 products listing pregnenolone give more (median 25 mg).

Source: NIH ODS Dietary Supplement Label Database, label 298259 (entered October 24, 2023), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: Take 1 capsule daily with or without food.
Warnings
Warning: This product is only intended for use in healthy adults 18 years of age or older.
Pregnant or nursing women should not use this product. Consult your healthcare provider before using this product, especially if you are taking any prescription, over the counter medication, dietary supplement product, or if you have any preexisting medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, seizure disorder, psychiatric disease, diabetes, difficulty urinating due to prostate enlargement or if you are taking a MAOI (Monoamine Oxidase Inhibitor) or any other medication.
Discontinue use and consult your health care professional if you experience adverse reaction to this product. Discontinue use 2 weeks prior to surgery. Do not exceed recommended serving. Do not use if safety seal is broken or missing.
Warning: This product is only intended for use in healthy adults 18 years of age or older. Keep out of reach of children.
Warning: Consuming this product can expose you to chemicals including lead, which is known to the Sate of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.
Storage
Protect from heat, light and moisture. Store at 10-25 Degrees Celsius (50-77 Degrees Fahrenheit)

Source: label statements in DSLD label 298259.

What else is on the label?

Other ingredients: Rice Flour, Hypromellose, Magnesium Stearate.

How many labels does Pregnenolone have?

2 labels are on file under this name since July 21, 2022: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 298259 (current) Entered October 24, 2023 · on the market · 90 vegetable caps · UPC 6 72975 31543 6
  2. Label 269442 Entered July 21, 2022 · off the market November 16, 2022 · 90 vegetable caps · UPC 6 72975 31543 6

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Core Nutritionals, LLC (distributor), Statesville, NC. All Core Nutritionals products.

Where next?