Advanced Shark Cartilage

by Physician's Signature · other (e.g. tea bag) · 90 caplets

  • On the market (NIH)
  • UPC 8 50008 82087 8
  • DSLD label 229493
  • Serving 1 caplet
  • 90 servings

Advanced Shark Cartilage by Physician's Signature lists 9 ingredients, 6 with an amount per serving of 1 caplet, such as 120 mg of calcium, 70 mg of phosphorus, 280 mg of shark cartilage and 250 mg of glucosamine HCl; 3 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on July 23, 2020.

What is in Advanced Shark Cartilage?

Each row as the label prints it, per serving of 1 caplet. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Advanced Shark Cartilage: Supplement Facts rows against the market (DSLD label 229493, January 2026 release)
IngredientAmount% DVAmong products listing it
Calcium120 mg9%Calcium in Advanced Shark Cartilage against 17,831 products120 mg per serving; the middle half of products list 50 mg to 252 mg, the median 115 mg.DV 1,300 mgUL 2,500 mg120 mg

Higher than 51% of 17,831 products listing calcium (median 115 mg). Per day at the most servings: 360 mg.

Phosphorus70 mg6%Phosphorus in Advanced Shark Cartilage against 3,786 products70 mg per serving; the middle half of products list 45 mg to 200 mg, the median 90 mg.DV 1,250 mgUL 4,000 mg70 mg

58% of 3,786 products listing phosphorus give more (median 90 mg). Per day at the most servings: 210 mg.

Shark Cartilage280 mgCartilage in Advanced Shark Cartilage against 199 products280 mg per serving; the middle half of products list 40 mg to 750 mg, the median 100 mg.280 mg

Higher than 58% of 199 products listing cartilage (median 100 mg). Per day at the most servings: 840 mg.

Glucosamine HCl250 mgGlucosamine Hydrochloride in Advanced Shark Cartilage against 628 products0.25 g per serving; the middle half of products list 0.75 g to 1.5 g, the median 1.5 g.0.25 g

91% of 628 products listing glucosamine hydrochloride give more (median 1.5 g). Per day at the most servings: 0.75 g.

Feverfew40 mgFeverfew in Advanced Shark Cartilage against 162 products40 mg per serving; the middle half of products list 50 mg to 380 mg, the median 200 mg.40 mg

77% of 162 products listing feverfew give more (median 200 mg). Per day at the most servings: 120 mg.

Proprietary Herbal Blend100 mg
Aloe veraAloe vera Genus: Aloe Species: vera Note: (20:1) (from)in the blend, no amount given
Aloe vera 200:1 extract9.5 mg
Boswelliaas Boswellic AcidBoswellia (Form: 40% Boswellic Acid) PlantPart: gum resin Genus: Boswelliain the blend, no amount given
Turmeric rhizome extractas CurcuminoidsTurmeric rhizome extract (Form: 95% Curcuminoids) PlantPart: rhizomein the blend, no amount given

Source: NIH ODS Dietary Supplement Label Database, label 229493 (entered July 23, 2020), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 91% of the 628 products that print an amount of glucosamine hydrochloride list more than its 0.25 g of glucosamine HCl (filed by NIH under glucosamine hydrochloride) (median 1.5 g).

The NIH database records 3 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Advanced Shark Cartilage's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: Take one caplet three times daily preferably with a meal or as directed by your healthcare provider.
Warnings
Caution: Consult your physician before taking if you are pregnant, nursing, or have any per-existing medical conditions.
Keep out of the reach of children
Do not use if seal is broken
Contains: Crustacean shellfish (shrimp, crab) and fish (shark).
Storage
Store in a cool, dry place

Source: label statements in DSLD label 229493.

What else is on the label?

Other ingredients: Dicalcium Phosphate, Microcrystalline Cellulose, Croscarmellose Sodium, Stearic Acid, Silica, Magnesium Stearate, Pharmaceutical Glaze.

How many labels does Advanced Shark Cartilage have?

2 labels are on file under this name since June 24, 2019: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 229493 (current) Entered July 23, 2020 · on the market · 90 caplets · UPC 8 50008 82087 8
  2. Label 204178 Entered June 24, 2019 · off the market April 21, 2020 · 100 caplets

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Vitamins Direct (USA), Inc. (distributor), West Palm Beach, FL. All Physician's Signature products.

Where next?