PlainVitamins

Opti-EPA 500

by Douglas Laboratories · softgel capsule · 60 softgels

  • On the market (NIH)
  • UPC 3 10539 00362 6
  • DSLD label 274091
  • Serving 1 softgel
  • 60 servings

Opti-EPA 500 by Douglas Laboratories lists 3 ingredients, 3 with an amount per serving of 1 softgel, such as 1,000 mg of marine lipid concentrate, beside 1 Nutrition Facts row (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on September 22, 2022.

What is in Opti-EPA 500?

Each row as the label prints it, per serving of 1 softgel. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Opti-EPA 500: Supplement Facts rows against the market (DSLD label 274091, January 2026 release)
IngredientAmount% DVAmong products listing it
Calories10 Calories
Total Fat1 g1%Fat (unspecified) in Opti-EPA 500 against 11,965 products1 g per serving; the middle half of products list 1 g to 2.5 g, the median 1.5 g.1 g

56% of 11,965 products listing fat (unspecified) give more (median 1.5 g).

Marine Lipid concentrateMarine Lipid concentrate Note: providing1,000 mgFish Oil in Opti-EPA 500 against 1,990 products1 g per serving; the middle half of products list 1 g to 2 g, the median 1.2 g.1 g

55% of 1,990 products listing fish oil give more (median 1.2 g).

Eicosapentaenoic Acid300 mgEPA (Eicosapentaenoic Acid) in Opti-EPA 500 against 3,134 products300 mg per serving; the middle half of products list 120 mg to 590 mg, the median 300 mg.300 mg

48% of 3,134 products listing EPA (eicosapentaenoic acid) give more (median 300 mg).

Docosahexaenoic Acid200 mgDHA in Opti-EPA 500 against 3,627 products200 mg per serving; the middle half of products list 104 mg to 400 mg, the median 232 mg.200 mg

54% of 3,627 products listing DHA give more (median 232 mg).

Source: NIH ODS Dietary Supplement Label Database, label 274091 (entered September 22, 2022), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Usage: As a dietary supplement, adults take 1 softgel daily or as directed by your health professional.
Warnings
Warning: If you are pregnant, nursing, have any health condition or taking any medication, consult your health professional before using this product.
Keep out of reach of children.
Use only if safety seal is intact.
Contains: Fish Oil (anchovy, sardine, mackerel)
Allergens and what it does not contain
Gluten-free, Non-GMO
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 274091.

What else is on the label?

Other ingredients: Gelatin Capsule, Glycerin, purified Water, natural Mixed Tocopherols.

How many labels does Opti-EPA 500 have?

4 labels are on file under this name since February 23, 2012: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 274091 (current) Entered September 22, 2022 · on the market · 60 softgels · UPC 3 10539 00362 6
  2. Label 245339 Entered February 25, 2021 · off the market March 22, 2022 · 60 softgels · UPC 3 10539 00362 6
  3. Label 232588 Entered August 23, 2020 · on the market · 250 softgels · UPC 3 10539 01786 9
  4. Label 5270 Entered February 23, 2012 · off the market January 20, 2012 · 250 softgels · UPC 3 10539 01786 9

DSLD also links this label to: Opti-EPA 500 Marine Lipid Concentrate (image difference, same product), Opti-EPA 500 Marine Lipid Concentrate (package size difference, same product), Opti-EPA 500 Marine Lipid Concentrate (package size difference, same product), Opti-EPA 500 Marine Lipid Concentrate (image difference, same product), Opti-EPA 500 Marine Lipid Concentrate (package size difference, same product), Opti-EPA 500 Marine Lipid Concentrate (image difference, same product), Opti-EPA 500 Marine Lipid Concentrate (package size difference, same product), Opti-EPA 500 Marine Lipid Concentrate (package size difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Douglas Laboratories (distributor), Pittsburgh, PA. All Douglas Laboratories products.

Where next?