OPC-3 (Oligomeric Proanthocyanidins)

by Isotonix · powder · 10.6 ounces

  • On the market (NIH)
  • UPC 8 48570 00374 4
  • DSLD label 313409
  • Serving 3.3 g (2 capfuls (6.6 g) per 150 lbs for the first 7-10 days; 1 capful (3.3 g) thereafter)
  • 90 servings

OPC-3 (Oligomeric Proanthocyanidins) by Isotonix lists 6 ingredients, 6 with an amount per serving of 3.3 g, such as 95 mg of potassium, 25 mg of grape seed extract, 25 mg of red wine extract and 25 mg of pycnogenol, beside 3 Nutrition Facts rows (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on June 20, 2024.

What is in OPC-3 (Oligomeric Proanthocyanidins)?

Each row as the label prints it, per serving of 3.3 g. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

OPC-3 (Oligomeric Proanthocyanidins): Supplement Facts rows against the market (DSLD label 313409, January 2026 release)
IngredientAmount% DVAmong products listing it
Calories10 Calories
Total Carbohydrates2 g1%Carbohydrate in OPC-3 (Oligomeric Proanthocyanidins) against 21,979 products2 g per serving; the middle half of products list 1 g to 6 g, the median 3 g.2 g

58% of 21,979 products listing carbohydrate give more (median 3 g).

Total Sugar2 gSugar in OPC-3 (Oligomeric Proanthocyanidins) against 11,807 products2 g per serving; the middle half of products list 1 g to 4 g, the median 2 g.2 g

48% of 11,807 products listing sugar give more (median 2 g).

added Sugars2 g4%
Potassiumas Potassium Bicarbonate95 mg2%Potassium in OPC-3 (Oligomeric Proanthocyanidins) against 11,614 products95 mg per serving; the middle half of products list 50 mg to 190 mg, the median 99 mg.DV 4,700 mg95 mg

54% of 11,614 products listing potassium give more (median 99 mg).

Grape seed extract25 mgGrape in OPC-3 (Oligomeric Proanthocyanidins) against 1,900 products25 mg per serving; the middle half of products list 25 mg to 100 mg, the median 50 mg.25 mg

69% of 1,900 products listing grape give more (median 50 mg).

Red Wine extract25 mgRed Wine in OPC-3 (Oligomeric Proanthocyanidins) against 115 products25 mg per serving; the middle half of products list 25 mg to 90 mg, the median 25 mg.25 mg

50% of 115 products listing red wine give more (median 25 mg).

Pycnogenolas Pine Bark Extract25 mgMaritime Pine in OPC-3 (Oligomeric Proanthocyanidins) against 215 products25 mg per serving; the middle half of products list 25 mg to 100 mg, the median 50 mg.25 mg

63% of 215 products listing maritime pine give more (median 50 mg).

Bilberry extract25 mgBilberry in OPC-3 (Oligomeric Proanthocyanidins) against 896 products25 mg per serving; the middle half of products list 20 mg to 100 mg, the median 50 mg.25 mg

63% of 896 products listing bilberry give more (median 50 mg).

Citrus Bioflavonoids Complex25 mgFlavonoid in OPC-3 (Oligomeric Proanthocyanidins) against 2,343 products25 mg per serving; the middle half of products list 25 mg to 100 mg, the median 50 mg.25 mg

66% of 2,343 products listing flavonoid give more (median 50 mg).

Source: NIH ODS Dietary Supplement Label Database, label 313409 (entered June 20, 2024), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with OPC-3 (Oligomeric Proanthocyanidins)'s, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions for use: Pour 1 level, white bottle capful of powder into the overcap. Add water to the line on the overcap (2 fl oz/60 ml) and stir. As a dietary supplement, take once daily or as directed by your healthcare provider. Take 2 servings per 150 pounds of body weight daily for the first 7-10 days, and take 1 servings thereafter as a maintenance program. Maximum absorption occurs when taken on an empty stomach. This product is isotonic only if the specified amounts of powder and water are used.
Warnings
Warning: If you are currently using prescription drugs, have an ongoing medical condition, or if you are pregnant or breastfeeding, consult your healthcare provider before using this product.
Keep out of the reach of children.
Do not use if safety seal is broken. Resale on third-party websites is strictly prohibited unless specifically authorized by Market America or its corporate affiliates. If barcodes are altered or you purchase this product from an unauthorized third-party website, the product is not guaranteed by Market America or its corporate affiliates.
Allergens and what it does not contain
This vegan product contains no added wheat, soy, yeast, gluten, artificial flavor, salt, preservatives or milk.
Gluten free
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 313409.

What else is on the label?

Other ingredients: Fructose, Glucose, Citric Acid, Maltodextrin, Silica, Calcium Sulfate, Food Starch, Modified, Apple Pectin, Stearic Acid.

How many labels does OPC-3 (Oligomeric Proanthocyanidins) have?

3 labels are on file under this name since April 23, 2020: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 313409 (current) Entered June 20, 2024 · on the market · 10.6 ounces · UPC 8 48570 00374 4
  2. Label 313408 Entered June 20, 2024 · on the market · 3.5 ounces · UPC 8 48570 00375 1
  3. Label 217993 Entered April 23, 2020 · off the market October 4, 2023 · 10.6 ozs

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Market America, Inc. (distributor), Greensboro, NC. All Isotonix products.

Where next?