Nitric Oxide MD +BioPerine

by Approved Science · capsule · 90 capsules

  • On the market (NIH)
  • UPC X00287O8LL
  • DSLD label 319800
  • Serving 3 capsules
  • 30 servings

Nitric Oxide MD +BioPerine by Approved Science lists 9 ingredients, 9 with an amount per serving of 3 capsules, such as 480 mg of L-citrulline, 30 mg of pine bark extract, 30 mg of quercetin and 30 mg of longjack extract. Its current label entered the NIH Dietary Supplement Label Database on November 22, 2024.

What is in Nitric Oxide MD +BioPerine?

Each row as the label prints it, per serving of 3 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Nitric Oxide MD +BioPerine: Supplement Facts rows against the market (DSLD label 319800, January 2026 release)
IngredientAmount% DVAmong products listing it
Nitri-Sci L-Arginine Blend1,680 mg
Arginine Alpha-Ketoglutarate1,350 mgArginine Alpha Ketoglutarate in Nitric Oxide MD +BioPerine against 322 products1.35 g per serving; the middle half of products list 0.75 g to 1.99 g, the median 1 g.1.35 g

Higher than 63% of 322 products listing arginine alpha ketoglutarate (median 1 g). Per day at the most servings: 2.7 g.

L-Arginine MonohydrateMONO255 mgArginine in Nitric Oxide MD +BioPerine against 1,455 products315 mg per serving; the middle half of products list 167 mg to 1,000 mg, the median 500 mg.315 mg

64% of 1,455 products listing arginine give more (median 500 mg). Per day at the most servings: 630 mg.

L-Arginine MalateMALATE60 mg
Arginine Ketoisocaproate15 mg
L-Citrulline480 mgCitrulline in Nitric Oxide MD +BioPerine against 1,209 products0.48 g per serving; the middle half of products list 1 g to 5 g, the median 3 g.0.48 g

88% of 1,209 products listing citrulline give more (median 3 g). Per day at the most servings: 0.96 g.

Pine Bark Extractas Pinus pinaster Bark Extract30 mgPine in Nitric Oxide MD +BioPerine against 220 products30 mg per serving; the middle half of products list 25 mg to 180 mg, the median 83 mg.30 mg

62% of 220 products listing pine give more (median 83 mg). Per day at the most servings: 60 mg.

Quercetinas Sophora japonica30 mgQuercetin in Nitric Oxide MD +BioPerine against 1,548 products30 mg per serving; the middle half of products list 26.5 mg to 250 mg, the median 100 mg.30 mg

70% of 1,548 products listing quercetin give more (median 100 mg). Per day at the most servings: 60 mg.

Longjack extract30 mgEurycoma Longifolia in Nitric Oxide MD +BioPerine against 496 products30 mg per serving; the middle half of products list 75 mg to 212.47 mg, the median 100 mg.30 mg

90% of 496 products listing eurycoma longifolia give more (median 100 mg). Per day at the most servings: 60 mg.

BioPerineas Piper nigrumstandardized to 95% piperine, standardized to 50:15 mgBlack Pepper in Nitric Oxide MD +BioPerine against 2,363 products5 mg per serving; the middle half of products list 5 mg to 10 mg, the median 5 mg.5 mg

33% of 2,363 products listing black pepper give more (median 5 mg). Per day at the most servings: 10 mg.

Source: NIH ODS Dietary Supplement Label Database, label 319800 (entered November 22, 2024), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 90% of the 496 products that print an amount of eurycoma longifolia list more than its 30 mg of longjack extract (filed by NIH under eurycoma longifolia) (median 100 mg).

The NIH database records 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Nitric Oxide MD +BioPerine's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: On workout days: Take 3 capsules before breakfast and 3 capsules, 30 minutes before a workout with an 8 oz. glass of water. On rest days: Take 3 capsules before breakfast and 3 capsules before dinner with an 8 oz. glass of water.
Warnings
Caution: Do not exceed recommended dose. Do not use if safety seal is damaged or missing.
Pregnant women or nursing mothers, children under 18, and individuals with a known medical condition, should consult with a physician before taking this or any other dietary supplement.
Pregnant women or nursing mothers, children under 18, and individuals with a known medical condition, should consult with a physician before taking this or any other dietary supplement. Keep out of reach of children.
Allergens and what it does not contain
Made with GMO free ingredients

Source: label statements in DSLD label 319800.

What else is on the label?

Other ingredients: Cellulose.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Vegan friendly Made in USA No animal testing GMP Good Manufacturing Practice Quality Product.

How many labels does Nitric Oxide MD +BioPerine have?

One label is on file, entered on November 22, 2024.

  1. Label 319800 (current) Entered November 22, 2024 · on the market · 90 capsules · UPC X00287O8LL

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Approved Science (distributor), New York, NY. All Approved Science products.

Where next?