Niasafe-600

by Thorne Research · capsule · 180 vegetarian capsules

  • Off the market since December 2019 (NIH)
  • UPC 6 93749 11402 4
  • DSLD label 73901
  • Serving 1 capsule

Niasafe-600 by Thorne Research lists one ingredient: 540 mg of niacin per serving of 1 capsule. Its current label entered the NIH Dietary Supplement Label Database on May 24, 2017.

What is in Niasafe-600?

Each row as the label prints it, per serving of 1 capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Niasafe-600: Supplement Facts rows against the market (DSLD label 73901, January 2026 release)
IngredientAmount% DVAmong products listing it
Niacinas Inositol HexanicotinateNiacin (Form: as Inositol Hexaniacinate Note: Does not cause flushing in many patients.)540 mg2,700%Niacin in Niasafe-600 against 12,413 products540 mg per serving; the middle half of products list 13.2 mg to 48 mg, the median 20 mg.DV 16 mgUL 35 mg540 mg

Higher than over 99% of 12,413 products listing niacin (median 20 mg). Per day at the most servings: 1,620 mg. 46.3 times the adult UL a day.

Source: NIH ODS Dietary Supplement Label Database, label 73901 (entered May 24, 2017), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • At 3 servings a day, the most its directions give, the label lists 1,620 mg of niacin, 46.3 times the adult Tolerable Upper Intake Level.

The NIH database records 1 to 3 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Use: Take 1 capsule one to three times daily or as recommended by your health-care practitioner.
Warnings
Tamper Evident: Use only if bottle is sealed.
If pregnant, consult your health-care practitioner before using this product.
Storage
Store tightly sealed in a cool, dry place.

Source: label statements in DSLD label 73901.

What else is on the label?

Other ingredients: Hypromellose (derived from Cellulose) Capsule, Leucine, Silicon Dioxide.

How many labels does Niasafe-600 have?

4 labels are on file under this name since November 21, 2012: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 73901 (current) Entered May 24, 2017 · off the market December 18, 2019 · 180 vegetarian capsules · UPC 6 93749 11402 4
  2. Label 35424 Entered July 25, 2014 · off the market December 18, 2019 · 60 vegetarian capsules · UPC 6 93749 11302 7
  3. Label 15700 Entered November 21, 2012 · off the market April 26, 2017 · 180 vegetarian capsules · UPC 6 93749 11402 4
  4. Label 15696 Entered November 21, 2012 · off the market June 26, 2014 · 60 vegetarian capsules · UPC 6 93749 11302 7

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Thorne Research, Inc. (manufacturer), Dover, Idaho. All Thorne Research products.

Where next?