PlainVitamins

Natural Collagen II Plus

by Roex · capsule · 90 capsules

  • Off the market since March 2022 (NIH)
  • UPC 6 45245 27090 2
  • DSLD label 211474
  • Serving 3 vegetable capsules
  • 30 servings

Natural Collagen II Plus by Roex lists 5 ingredients, 5 with an amount per serving of 3 vegetable capsules, such as 1,500 mg of BioCell collagen and 500 mg of chondroitin sulfate sodium. Its current label entered the NIH Dietary Supplement Label Database on January 25, 2020.

What is in Natural Collagen II Plus?

Each row as the label prints it, per serving of 3 vegetable capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Natural Collagen II Plus: Supplement Facts rows against the market (DSLD label 211474, January 2026 release)
IngredientAmount% DVAmong products listing it
BioCell Collagen1,500 mgCollagen in Natural Collagen II Plus against 1,008 products1.5 g per serving; the middle half of products list 0.1 g to 4.2 g, the median 1 g.1.5 g

Higher than 59% of 1,008 products listing collagen (median 1 g).

Hydrolyzed Collagen Type II900 mg
Chondroitin Sulfate300 mg
Hyaluronic Acid150 mgHyaluronic acid in Natural Collagen II Plus against 900 products150 mg per serving; the middle half of products list 10 mg to 100 mg, the median 50 mg.150 mg

Higher than 94% of 900 products listing hyaluronic acid (median 50 mg).

Chondroitin Sulfate Sodiumas Bovine500 mgChondroitin Sulfate in Natural Collagen II Plus against 950 products500 mg per serving; the middle half of products list 200 mg to 1,200 mg, the median 400 mg.500 mg

Higher than 53% of 950 products listing chondroitin sulfate (median 400 mg).

Source: NIH ODS Dietary Supplement Label Database, label 211474 (entered January 25, 2020), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • Its 150 mg of hyaluronic acid is higher than 94% of the 900 hyaluronic acid products that print an amount; 35 list more.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: Adults, take 3 capsules once daily preferably twenty minutes before eating as a dietary supplement or as directed by your doctor.
Warnings
Warning: Consult your physician prior to use if you are pregnant, nursing, have a medical condition or are taking medications.
Not intended for children.
Keep out of the reach of children.
Do not use if clear safety seal around bottle neck is broken or missing.
Storage
Store at room temperature, in a dry place.

Source: label statements in DSLD label 211474.

What else is on the label?

Other ingredients: Vegetable Cellulose, Magnesium Stearate, Silica.

How many labels does Natural Collagen II Plus have?

One label is on file, entered on January 25, 2020.

  1. Label 211474 (current) Entered January 25, 2020 · off the market March 3, 2022 · 90 capsules · UPC 6 45245 27090 2

DSLD also links this label to: Collagen II Plus (image difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names BIN Science LLC (distributor), Englewood, CO, United States of America. All Roex products.

Where next?