Nattosyn

by Douglas Laboratories · capsule · 60 vegetarian capsules

  • On the market (NIH)
  • UPC 3 10539 02240 5
  • DSLD label 237131
  • Serving 1 to 2 vegetarian capsules; amounts per 1 vegetarian capsule
  • 60 servings

Nattosyn by Douglas Laboratories lists 3 ingredients, 3 with an amount per serving of 1 vegetarian capsule, such as 100 mg of hesperidin methyl chalcone, 50 mg of nattokinase and 50 mg of standardized pomegranate extract. Its current label entered the NIH Dietary Supplement Label Database on October 23, 2020.

What is in Nattosyn?

Each row as the label prints it, per serving of 1 vegetarian capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Nattosyn: Supplement Facts rows against the market (DSLD label 237131, January 2026 release)
IngredientAmount% DVAmong products listing it
Hesperidin Methyl Chalcone100 mgHesperidin in Nattosyn against 552 products100 mg per serving; the middle half of products list 10 mg to 50 mg, the median 20 mg.100 mg

Higher than 79% of 552 products listing hesperidin (median 20 mg). Per day at the most servings: 200 mg.

Nattokinaseas SoyNattokinase (Form: from Soy) (Alt. Name: NSK-SD) Note: 1,000 FU50 mgNattokinase in Nattosyn against 141 products50 mg per serving; the middle half of products list 50 mg to 100 mg, the median 100 mg.50 mg

67% of 141 products listing nattokinase give more (median 100 mg). Per day at the most servings: 100 mg.

Standardized Pomegranate extractas Ellagic AcidStandardized Pomegranate extract (Form: standardized to 40% Ellagic Acid) PlantPart: pericarp50 mgPomegranate in Nattosyn against 860 products50 mg per serving; the middle half of products list 12.5 mg to 250 mg, the median 70.5 mg.50 mg

51% of 860 products listing pomegranate give more (median 70.5 mg). Per day at the most servings: 100 mg.

Source: NIH ODS Dietary Supplement Label Database, label 237131 (entered October 23, 2020), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records 1 to 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Nattosyn's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Usage: As a dietary supplement, adults take 1-2 capsule, 1-2 times daily or as directed by your health professional.
Warnings
Warning: Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use.
Keep out of the reach of children.
Use only if safety seal is intact.
Contains: Soy
Allergens and what it does not contain
Gluten-free, Non-GMO
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 237131.

What else is on the label?

Other ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Silica, Vegetable Stearate.

How many labels does Nattosyn have?

3 labels are on file under this name since February 23, 2012: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 237131 (current) Entered October 23, 2020 · on the market · 60 vegetarian capsules · UPC 3 10539 02240 5
  2. Label 57543 Entered March 24, 2016 · off the market July 31, 2020 · 60 Vegetarian Capsules · UPC 3 10539 02240 5
  3. Label 5227 Entered February 23, 2012 · off the market December 15, 2015 · 60 Vegetarian Capsules · UPC 3 10539 02240 5

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Douglas Laboratories (manufacturer), Pittsburgh, PA. All Douglas Laboratories products.

Where next?