PlainVitamins

MSM with OptiMSM 1000 mg

by Doctor's Best · capsule · 180 veggie caps

  • On the market (NIH)
  • UPC 7 53950 00331 6
  • DSLD label 302691
  • Serving 3 capsules
  • 60 servings

MSM with OptiMSM 1000 mg by Doctor's Best lists one ingredient: 300 mg of OptiMSM per serving of 3 capsules. Its current label entered the NIH Dietary Supplement Label Database on June 20, 2024.

What is in MSM with OptiMSM 1000 mg?

Each row as the label prints it, per serving of 3 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

MSM with OptiMSM 1000 mg: Supplement Facts rows against the market (DSLD label 302691, January 2026 release)
IngredientAmount% DVAmong products listing it
OptiMSMas Methylsulfonylmethane300 mgMethylsulfonylmethane in MSM with OptiMSM 1000 mg against 1,454 products300 mg per serving; the middle half of products list 150 mg to 1,000 mg, the median 500 mg.300 mg

56% of 1,454 products listing methylsulfonylmethane give more (median 500 mg).

Source: NIH ODS Dietary Supplement Label Database, label 302691 (entered June 20, 2024), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

  • MSM 450 mgTerraVita Premium Collection same ingredients
  • MSMSundown Naturals · off the market same ingredients
  • MSM 500 mgSundown Naturals same ingredients
  • MSM 500 mgIndiana Botanic Gardens same ingredients
  • MSM 500 mgBotanic Choice same ingredients
  • MSM 500 mgStandard Vitamins · off the market same ingredients

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested adults use: Take 3 capsules daily with food, or as recommended by a nutritionally informed physician.
Warnings
Warning: If you are pregnant or lactating, consult your physician before using any health supplement.
Allergens and what it does not contain
Non-GMO / Gluten Free / Vegan
Storage
Store in a cool dry place.

Source: label statements in DSLD label 302691.

What else is on the label?

Other ingredients: Hypromellose.

How many labels does MSM with OptiMSM 1000 mg have?

4 labels are on file under this name since May 28, 2019: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 302691 (current) Entered June 20, 2024 · on the market · 180 veggie caps · UPC 7 53950 00331 6
  2. Label 203185 Entered May 28, 2019 · off the market March 28, 2025 · 180 veggie caps · UPC 7 53950 00331 6
  3. Label 203181 Entered May 28, 2019 · on the market · 360 capsules · UPC 7 53950 00317 0
  4. Label 202773 Entered May 28, 2019 · on the market · 180 capsules · UPC 7 53950 00064 3

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Doctor's Best, Inc. (distributor), Tustin, California. All Doctor's Best products.

Where next?