MSM Joint Formula

by Natural Factors · capsule · 90 capsules

  • On the market (NIH)
  • UPC 0 68958 02695 4
  • DSLD label 282400
  • Serving 1 capsule
  • 90 servings

MSM Joint Formula by Natural Factors lists 3 ingredients, 3 with an amount per serving of 1 capsule, such as 300 mg of glucosamine sulfate, 300 mg of OptiMSM methyl-sulfonyl-methane and 240 mg of chondroitin sulfate, beside 1 Nutrition Facts row (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on February 21, 2023.

What is in MSM Joint Formula?

Each row as the label prints it, per serving of 1 capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

MSM Joint Formula: Supplement Facts rows against the market (DSLD label 282400, January 2026 release)
IngredientAmount% DVAmong products listing it
Sodium25 mg1%Sodium in MSM Joint Formula against 14,514 products25 mg per serving; the middle half of products list 15 mg to 142 mg, the median 55 mg.25 mg

64% of 14,514 products listing sodium give more (median 55 mg). Per day at the most servings: 150 mg.

Glucosamine Sulfateas Shellfish300 mgGlucosamine Sulfate in MSM Joint Formula against 875 products0.3 g per serving; the middle half of products list 0.5 g to 1.5 g, the median 1 g.0.3 g

88% of 875 products listing glucosamine sulfate give more (median 1 g). Per day at the most servings: 1.8 g.

OptiMSM Methyl-Sulfonyl-Methane300 mgMethylsulfonylmethane in MSM Joint Formula against 1,454 products300 mg per serving; the middle half of products list 150 mg to 1,000 mg, the median 500 mg.300 mg

56% of 1,454 products listing methylsulfonylmethane give more (median 500 mg). Per day at the most servings: 1,800 mg.

Chondroitin Sulfateas Bovine source240 mgChondroitin Sulfate in MSM Joint Formula against 950 products240 mg per serving; the middle half of products list 200 mg to 1,200 mg, the median 400 mg.240 mg

65% of 950 products listing chondroitin sulfate give more (median 400 mg). Per day at the most servings: 1,440 mg.

Source: NIH ODS Dietary Supplement Label Database, label 282400 (entered February 21, 2023), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records 4 to 6 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

2 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Usage: 1 capsule 4-6 times per day or as directed by a health professional.
Warnings
Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding, or trying to conceive, or if you are taking medication, have a medical condition, or anticipate a surgery.
Keep out of the reach of children.
Sealed for your protection. Do not use if seal is broken.
Contains shellfish (shrimp and crab).
Allergens and what it does not contain
Contains no artificial colors, preservatives, or sweeteners; no dairy, sugar, wheat, gluten, yeast, soy, corn, egg, fish, tree nuts, or GMOs.
Storage
For freshness, store in a cool, dry place.

Source: label statements in DSLD label 282400.

What else is on the label?

Other ingredients: Gelatin, Water, Purified, Magnesium Stearate, Rice, Powder.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): ISURA Non-GMO Mass Spec Documentation Lab tested.

How many labels does MSM Joint Formula have?

7 labels are on file under this name since June 1, 2012: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 282400 (current) Entered February 21, 2023 · on the market · 90 capsules · UPC 0 68958 02695 4
  2. Label 220602 Entered May 22, 2020 · on the market · 180 capsules · UPC 0 68958 02696 1
  3. Label 220598 Entered May 22, 2020 · off the market February 10, 2022 · 90 capsules · UPC 0 68958 02695 4
  4. Label 51628 Entered October 22, 2015 · off the market April 7, 2020 · 180 capsules · UPC 0 68958 02696 1
  5. Label 51591 Entered October 22, 2015 · off the market April 7, 2020 · 90 capsules · UPC 0 68958 02695 4
  6. Label 8874 Entered June 1, 2012 · off the market September 16, 2015 · 180 capsules · UPC 0 68958 02696 1
  7. Label 8872 Entered June 1, 2012 · off the market September 16, 2015 · 90 capsules · UPC 0 68958 02695 4

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Natural Factors (manufacturer), Monroe, WA. All Natural Factors products.

Where next?