PlainVitamins

MSM & Glucosamine Sulfate

by Natural Factors · capsule · 180 capsules

  • On the market (NIH)
  • UPC 0 68958 02699 2
  • DSLD label 282399
  • Serving 1 capsule
  • 180 servings

MSM & Glucosamine Sulfate by Natural Factors lists 2 ingredients, 2 with an amount per serving of 1 capsule, such as 500 mg of OptiMSM and 375 mg of glucosamine sulfate. Its current label entered the NIH Dietary Supplement Label Database on February 21, 2023.

What is in MSM & Glucosamine Sulfate?

Each row as the label prints it, per serving of 1 capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

MSM & Glucosamine Sulfate: Supplement Facts rows against the market (DSLD label 282399, January 2026 release)
IngredientAmount% DVAmong products listing it
OptiMSMas Methylsulfonylmethane500 mgMethylsulfonylmethane in MSM & Glucosamine Sulfate against 1,454 products500 mg per serving; the middle half of products list 150 mg to 1,000 mg, the median 500 mg.500 mg

36% of 1,454 products listing methylsulfonylmethane give more (median 500 mg). Per day at the most servings: 2,000 mg.

Glucosamine Sulfateas ShellfishShrimp and Crab375 mgGlucosamine Sulfate in MSM & Glucosamine Sulfate against 875 products0.375 g per serving; the middle half of products list 0.5 g to 1.5 g, the median 1 g.0.375 g

87% of 875 products listing glucosamine sulfate give more (median 1 g). Per day at the most servings: 1.5 g.

Source: NIH ODS Dietary Supplement Label Database, label 282399 (entered February 21, 2023), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records 2 to 4 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested usage: 1 capsule 2–4 times per day or as directed by a health professional.
Warnings
Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding, or trying to conceive, or if you are taking medication, have a medical condition, or anticipate a surgery.
Keep out of the reach of children.
Sealed for your protection. Do not use if seal is broken.
Contains shellfish (shrimp and crab).
Allergens and what it does not contain
Contains no artificial colors, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, salt, tree nuts, or GMOs.
Storage
For freshness, store in a cool, dry place.

Source: label statements in DSLD label 282399.

What else is on the label?

Other ingredients: Gelatin capsule, Magnesium Stearate, Silica.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): ISURA Non-GMO Mass Spec Documentation Lab tested; Purity & Potency Guaranteed.

How many labels does MSM & Glucosamine Sulfate have?

5 labels are on file under this name since June 1, 2012: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 282399 (current) Entered February 21, 2023 · on the market · 180 capsules · UPC 0 68958 02699 2
  2. Label 51635 Entered October 22, 2015 · off the market February 10, 2022 · 180 capsules · UPC 0 68958 02699 2
  3. Label 51632 Entered October 22, 2015 · on the market · 90 capsules · UPC 0 68958 02698 5
  4. Label 8878 Entered June 25, 2012 · off the market September 16, 2015 · 180 capsules · UPC 0 68958 02699 2
  5. Label 8877 Entered June 1, 2012 · on the market · 90 capsules · UPC 0 68958 02698 5

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Natural Factors Canada (manufacturer). All Natural Factors products.

Where next?