PlainVitamins

Melatonin + 5-HTP Advanced Time Release

by Natrol · tablet or pill · 60 bi-layer tablets

  • On the market (NIH)
  • UPC 0 47469 07229 2
  • DSLD label 332279
  • Serving 1 tablet
  • 60 servings

Melatonin + 5-HTP Advanced Time Release by Natrol lists 4 ingredients, 4 with an amount per serving of 1 tablet, such as 10 mg of vitamin B6, 97 mg of calcium, 50 mg of 5-hydroxytryptophan and 6 mg of melatonin. Its current label entered the NIH Dietary Supplement Label Database on June 25, 2025.

What is in Melatonin + 5-HTP Advanced Time Release?

Each row as the label prints it, per serving of 1 tablet. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Melatonin + 5-HTP Advanced Time Release: Supplement Facts rows against the market (DSLD label 332279, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin B6as Pyridoxine Hydrochloride10 mg588%Vitamin B6 in Melatonin + 5-HTP Advanced Time Release against 15,277 products10 mg per serving; the middle half of products list 2 mg to 20 mg, the median 6 mg.DV 1.7 mgUL 100 mg10 mg

Higher than 55% of 15,277 products listing vitamin B6 (median 6 mg).

Calciumas Dibasic Calcium Phosphate97 mg7%Calcium in Melatonin + 5-HTP Advanced Time Release against 17,831 products97 mg per serving; the middle half of products list 50 mg to 252 mg, the median 115 mg.DV 1,300 mgUL 2,500 mg97 mg

58% of 17,831 products listing calcium give more (median 115 mg).

5-Hydroxytryptophanas Griffonia simplicifolia50 mg5-HTP in Melatonin + 5-HTP Advanced Time Release against 676 products50 mg per serving; the middle half of products list 50 mg to 100 mg, the median 100 mg.50 mg

55% of 676 products listing 5-HTP give more (median 100 mg).

Melatonin6 mgMelatonin in Melatonin + 5-HTP Advanced Time Release against 1,557 products6 mg per serving; the middle half of products list 2 mg to 5 mg, the median 3 mg.6 mg

Higher than 83% of 1,557 products listing melatonin (median 3 mg).

Source: NIH ODS Dietary Supplement Label Database, label 332279 (entered June 25, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Melatonin + 5-HTP Advanced Time Release's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested use: Adults take 1 tablet 30 minutes before bedtime.
Warnings
Warning: Not intended for individuals under the age of 18 years.
This product is not intended to treat insomnia or other sleep disorder.
Consult a physician before using this product if taking medication, including drugs for depression, migraine, Parkinsons disease or psychiatric disorder, or if you are using any tranquilizers or sedatives, have any medical condition, are pregnant or lactating, have an autoimmune condition or depressive disorder.
Melatonin may cause drowsiness or sleepiness, do not take when driving or operating heavy machinery, or consuming alcohol. Do not use with other supplements containing L-Tryptophan or 5-HTP. If adverse reactions occur, discontinue use. For occasional short-term use only. Use only as directed and do not exceed suggested use. This product should never substitute healthy sleep practices.
Keep out of reach of children.
Do not use if safety seal is damaged or missing.
Allergens and what it does not contain
100% Drug free
No: Milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat, soybeans, sesame.
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 332279.

What else is on the label?

Other ingredients: Microcrystalline Cellulose, Hypromellose, Silicon Dioxide, Stearic Acid, Maltodextrin, Beet Root Extract, Cellulose Gum, Magnesium Stearate, Methylcellulose, Glycerin.

How many labels does Melatonin + 5-HTP Advanced Time Release have?

One label is on file, entered on June 25, 2025.

  1. Label 332279 (current) Entered June 25, 2025 · on the market · 60 bi-layer tablets · UPC 0 47469 07229 2

DSLD also links this label to: Advanced Sleep Melatonin + 5-HTP (image difference, same product), Advanced Sleep Melatonin + 5-HTP Time Release (image difference, same product), Advanced Sleep Melatonin + 5-HTP Time Release (image difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Natrol LLC (distributor), Sherman Oaks, CA. All Natrol products.

Where next?