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Enzymatic Therapy · Non-Nutrient/Non-Botanical supplement

Mega-Zyme Systemic Enzymes

17 ingredients on file in the NIH Dietary Supplement Label Database. Off-market, label data preserved for reference.

17
Ingredients
7
Nutrient categories
Top 21%
By ingredient count

Mega-Zyme Systemic Enzymes is a non-nutrient/non-botanical supplement by Enzymatic Therapy in tablet or pill form, listing 17 ingredients in the NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. Currently listed as off-market (no longer available for purchase, but label data is preserved). Daily Value percentages shown below are based on FDA reference daily intake amounts for adults.

Product Details

Form
Tablet or Pill
Database Entry Date
2014-11-25
Ingredients
17

Supplement Facts (17 Ingredients)

Ingredient Group Amount % DV
Pancreatic Enzymes Blend (Metabolite, constituent, extract, isolate, or combination of these) Not disclosed on label No DV
Protease Proteolytic Enzymes (Proteases) Not disclosed on label No DV
Amylase Amylase Not disclosed on label No DV
Lipase Lipase Not disclosed on label No DV
Trypsin Trypsin Not disclosed on label No DV
Papain Papain Not disclosed on label No DV
Bromelain Bromelain Not disclosed on label No DV
Lysozyme Lysozyme Not disclosed on label No DV
Chymotrypsin Chymotrypsin Not disclosed on label No DV
Cellulose Cellulose Not disclosed on label No DV
Potassium Bicarbonate Potassium Bicarbonate Not disclosed on label No DV
Modified Cellulose Cellulose Not disclosed on label No DV
modified Cellulose Gum Cellulose Not disclosed on label No DV
Magnesium Stearate Magnesium Not disclosed on label No DV
Silicon Dioxide Silicon Not disclosed on label No DV
Soy Lecithin lecithin Not disclosed on label No DV
Carnauba Wax Carnauba wax Not disclosed on label No DV

How does Mega-Zyme Systemic Enzymes compare?

Ingredients listed on each label, against the non-nutrient/non-botanical category average of 6.9. Data from the NIH DSLD.

Mega-Zyme Systemic Enzymes17
1 Andro Stenelone9
Non-Nutrient/Non-Botanical average6.9

Mega-Zyme Systemic Enzymes lists 8 ingredients more than 1 Andro Stenelone. That is 10 above the non-nutrient/non-botanical average.

What the Label Data Shows

With 17 ingredients on the label, Mega-Zyme Systemic Enzymes is one of the more extensive non-nutrient/non-botanical supplement formulas from Enzymatic Therapy in the NIH Dietary Supplement Label Database (DSLD), sold in tablet or pill form. These ingredients span 7 nutrient categories, enzyme, other, mineral, blend, and 3 more, reflecting a multi-component formula rather than a single-nutrient product.

Across a broader 17-ingredient formula, 17 of 17 carry no FDA reference-intake value, typical for a formula this size: larger blends tend to pull in botanicals, amino acids, and specialty compounds without an assigned Daily Value. Breadth like this isn't a red flag by itself.

Market status matters for supplement research. This product is currently listed as off-market in the DSLD, with its label first entered into the database on 2014-11-25. An off-market listing means production and distribution under this label have stopped, but the DSLD does not delete the entry, it stays on file for historical reference and formulation-history tracking.

About the DSLD database

The DSLD is a label database, not an FDA approval list, under the 1994 DSHEA framework, dietary supplements do not require pre-market approval, and label information reflects what manufacturers self-declare rather than independent laboratory verification. This page presents factual label data for reference only and is not medical advice; consult a licensed healthcare provider before making decisions about any supplement.

Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD) Supplement label data for Mega-Zyme Systemic Enzymes: ingredients, % Daily Value, market status, brand · 2026 DSLD captures manufacturer-self-declared label information; the NIH does not verify accuracy or evaluate safety/efficacy. Dietary supplements are regulated under DSHEA 1994, no pre-market FDA approval is required.

Ingredient Breakdown by Category

enzyme
8
Protease, Amylase, Lipase, +5 more
other
3
Potassium Bicarbonate, Modified Cellulose, modified Cellulose Gum
mineral
2
Magnesium Stearate, Silicon Dioxide
blend
1
Pancreatic Enzymes
fiber
1
Cellulose
fat
1
Soy Lecithin
non-nutrient/non-botanical
1
Carnauba Wax

Daily Value Coverage

0
Above 100% DV
0
Below 100% DV
17
No DV Established

Frequently Asked Questions

What ingredients are in Mega-Zyme Systemic Enzymes?
Mega-Zyme Systemic Enzymes contains 17 ingredients. Ingredients span 7 categories: enzyme, other, mineral, blend, fiber, fat, non-nutrient/non-botanical.
Who manufactures Mega-Zyme Systemic Enzymes?
Mega-Zyme Systemic Enzymes is was manufactured by Enzymatic Therapy. It is classified as a Non-Nutrient/Non-Botanical supplement in tablet or pill form.
Is Mega-Zyme Systemic Enzymes still available for purchase?
According to the NIH DSLD database, Mega-Zyme Systemic Enzymes is listed as off-market and may no longer be available for purchase.
What is the serving size of Mega-Zyme Systemic Enzymes?
The serving size is not specified.
What type of supplement is Mega-Zyme Systemic Enzymes?
Mega-Zyme Systemic Enzymes is classified as a "Non-Nutrient/Non-Botanical" supplement in the NIH database. This category includes products primarily composed of non-nutrient/non-botanical ingredients. DSLD sorts every supplement into one of 9 categories overall: Vitamin, Mineral, Botanical, Amino Acid & Protein, Non-Nutrient, Fat & Fatty Acid, Multi-Vitamin & Mineral, Botanical with Nutrients, or Other Combinations.
Data Sources & Methodology

Data as of 2025. Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD).

Supplement label data sourced from the Source: NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. The DSLD contains label information from dietary supplement products marketed in the United States.

Daily Value (DV) percentages are based on Source: FDA 21 CFR 101.9 Reference Daily Intake (RDI) values for adults. Products marked "Off Market" may no longer be available for purchase but their label data remains in the database for reference.

Disclaimer, Not Medical Advice

Label data from the Source: NIH Dietary Supplement Label Database (DSLD). This information is for educational and reference purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting, stopping, or combining any dietary supplement, especially if you are pregnant, nursing, take prescription medication, or have a medical condition.

Every figure on PlainVitamins is rendered directly from the NIH Dietary Supplement Label Database (DSLD), no number is typed in by an editor. This page draws directly on the NIH DSLD, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.