PlainVitamins

MacuGuard Ocular Support with Saffron

by Life Extension · softgel capsule · 60 softgels

  • On the market (NIH)
  • UPC 7 37870 19926 7
  • DSLD label 328563
  • Serving 1 softgel
  • 60 servings

MacuGuard Ocular Support with Saffron by Life Extension lists 8 ingredients, 5 with an amount per serving of 1 softgel, such as 20 mg of saffron stigma extract and 2.2 mg of cyanidin-3-glucoside; 3 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on May 21, 2025.

What is in MacuGuard Ocular Support with Saffron?

Each row as the label prints it, per serving of 1 softgel. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

MacuGuard Ocular Support with Saffron: Supplement Facts rows against the market (DSLD label 328563, January 2026 release)
IngredientAmount% DVAmong products listing it
MacuGuard Proprietary Blend173 mg
Phospholipidsin the blend, no amount given
Marigold Flower Extractas Tagetes erecta Flower Extractin the blend, no amount given
Luteinfree10 mgLutein in MacuGuard Ocular Support with Saffron against 2,493 products10 mg per serving; the middle half of products list 0.5 mg to 10 mg, the median 3 mg.10 mg

Higher than 71% of 2,493 products listing lutein (median 3 mg).

Meso-Zeaxanthin4 mgZeaxanthin in MacuGuard Ocular Support with Saffron against 1,215 products4 mg per serving; the middle half of products list 0.4 mg to 2 mg, the median 1 mg.4 mg

Higher than 81% of 1,215 products listing zeaxanthin (median 1 mg).

Trans-Zeaxanthinno amount given
Mixed Carotenoidsin the blend, no amount given
Alpha-Carotene1.24 mgAlpha-carotene in MacuGuard Ocular Support with Saffron against 73 products1,240 mcg per serving; the middle half of products list 250 mcg to 1,240 mcg, the median 555 mcg.1,240 mcg

Higher than 74% of 73 products listing alpha-carotene (median 555 mcg).

Saffron Stigma Extract20 mgSaffron in MacuGuard Ocular Support with Saffron against 201 products20 mg per serving; the middle half of products list 20 mg to 88.5 mg, the median 30 mg.20 mg

68% of 201 products listing saffron give more (median 30 mg).

Cyanidin-3-Glucosideas European Black Currant Fruit Extract2.2 mg

Source: NIH ODS Dietary Supplement Label Database, label 328563 (entered May 21, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient; 3 ingredients sit inside a blend, so their amounts cannot be compared.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with MacuGuard Ocular Support with Saffron's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: Take one (1) softgel daily, with food, or as recommended by a healthcare practitioner.
1 daily
Warnings
Read the entire label and follow the directions carefully prior to use. Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.
Warnings: Keep out of reach of children.
When using nutritional supplements, please consult with your physician if you are underdoing treatment for a medical condition or if you are pregnant or lactating.
To report a serious adverse event or obtain product information, contact 1-866-280-2852.
Allergens and what it does not contain
Gluten free Non GMO LE Certified
Storage
Store tightly closed in a cool, dry place.

Source: label statements in DSLD label 328563.

What else is on the label?

Other ingredients: Extra Virgin Olive Oil, Gelatin, Glycerin, Safflower Oil, Beeswax, Palm Oil, Water, Purified, Acacia Gum, Maltodextrin, Annatto.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Non GMO LE Certified.

How many labels does MacuGuard Ocular Support with Saffron have?

6 labels are on file under this name since May 24, 2017: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 328563 (current) Entered May 21, 2025 · on the market · 60 softgels · UPC 7 37870 19926 7
  2. Label 239978 Entered November 21, 2020 · off the market August 9, 2023 · 60 softgels
  3. Label 232625 Entered August 23, 2020 · off the market August 9, 2023 · 60 softgels · UPC 7 37870 19926 7
  4. Label 232196 Entered August 23, 2020 · off the market July 14, 2020 · 60 softgels · UPC 7 37870 19926 7
  5. Label 182214 Entered October 25, 2018 · off the market August 9, 2023 · 60 softgels · UPC 7 37870 19926 7
  6. Label 74005 Entered May 24, 2017 · off the market May 3, 2018 · 60 softgels · UPC 7 37870 19926 7

DSLD also links this label to: MacuGuard Ocular Support With Astaxanthin (image difference, same product), MacuGuard Ocular Support With Astaxanthin (image difference, same product), MacuGuard Ocular Support With Astaxanthin (image difference, same product), MacuGuard (image difference, same product), MacuGuard (image difference, same product), MacuGuard (image difference, same product), MacuGuard Ocular Support (image difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Quality Supplements and Vitamins, Inc. (distributor), Ft. Lauderdale, FL. All Life Extension products.

Where next?