PlainVitamins

Liver Optimizer

by Jarrow Formulas · tablet or pill · 90 tablets

  • Off the market since January 2024 (NIH)
  • UPC 7 90011 29012 4
  • DSLD label 243364
  • Serving 3 tablets
  • 30 servings

Liver Optimizer by Jarrow Formulas lists 9 ingredients, 9 with an amount per serving of 3 tablets, such as 15 mg of thiamine, 10 mg of vitamin B6, 100 mcg of biotin and 250 mg of milk thistle seed 30:1 extract. Its current label entered the NIH Dietary Supplement Label Database on March 25, 2021.

What is in Liver Optimizer?

Each row as the label prints it, per serving of 3 tablets. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Liver Optimizer: Supplement Facts rows against the market (DSLD label 243364, January 2026 release)
IngredientAmount% DVAmong products listing it
Thiamineas Thiamine Mononitrate, Vitamin B1Thiamin (Form: as Thiamine Mononitrate) (Alt. Name: vitamin B1)15 mg1,200%Thiamin in Liver Optimizer against 9,830 products15 mg per serving; the middle half of products list 1.5 mg to 25 mg, the median 5 mg.DV 1.2 mg15 mg

Higher than 66% of 9,830 products listing thiamin (median 5 mg).

Vitamin B6as Pyridoxine HydrochlorideVitamin B6 (Form: as Pyridoxine HCl)10 mg590%Vitamin B6 in Liver Optimizer against 15,277 products10 mg per serving; the middle half of products list 2 mg to 20 mg, the median 6 mg.DV 1.7 mgUL 100 mg10 mg

Higher than 55% of 15,277 products listing vitamin B6 (median 6 mg).

Biotinas D-BiotinBiotin (Form: as D-Biotin)100 mcg330%Biotin in Liver Optimizer against 9,447 products100 mcg per serving; the middle half of products list 50 mcg to 300 mcg, the median 200 mcg.DV 30 mcg100 mcg

61% of 9,447 products listing biotin give more (median 200 mcg).

Milk Thistle seed 30:1 extractas Total FlavonoidsMilk Thistle seed 30:1 extract (Form: 80% Total Flavonoids Note: 200 mg) PlantPart: seed Genus: Silybum Species: marianum250 mgMilk Thistle in Liver Optimizer against 1,277 products250 mg per serving; the middle half of products list 90 mg to 300 mg, the median 175 mg.250 mg

Higher than 62% of 1,277 products listing milk thistle (median 175 mg).

NAC300 mgN-Acetyl Cysteine in Liver Optimizer against 1,259 products300 mg per serving; the middle half of products list 55 mg to 500 mg, the median 150 mg.300 mg

Higher than 67% of 1,259 products listing N-acetyl cysteine (median 150 mg).

R-Alpha Lipoic Acidas Sodium R-Alpha LipoateR-Alpha Lipoic Acid (Form: from 125 mg Sodium R-Alpha Lipoate (Alt. Name: Bio-Enhanced Na-RALA))100 mgAlpha Lipoic Acid in Liver Optimizer against 2,407 products100 mg per serving; the middle half of products list 25 mg to 150 mg, the median 50 mg.100 mg

Higher than 56% of 2,407 products listing alpha lipoic acid (median 50 mg).

Artichoke leaf extractas Total Caffeoylquinic AcidsArtichoke leaf extract (Form: 5% Total Caffeoylquinic Acids Note: 10 mg) PlantPart: leaf Genus: Cynara Species: scolymus Classifier: L.200 mgArtichoke in Liver Optimizer against 433 products200 mg per serving; the middle half of products list 50 mg to 250 mg, the median 100 mg.200 mg

Higher than 67% of 433 products listing artichoke (median 100 mg).

Uridine 5'-Monophosphate100 mgUridine monophosphate in Liver Optimizer against 32 products100 mg per serving; the middle half of products list 68.75 mg to 250 mg, the median 200 mg.100 mg

69% of 32 products listing uridine monophosphate give more (median 200 mg).

Sulforaphane Glucosinolateas Brassica oleracea L. italica seed extractSulforaphane Glucosinolate (Form: from Brassica oleracea L. italica seed extract PlantPart: seed Genus: Brassica Species: oleracea Classifier: L.)5 mgGlucoraphanin in Liver Optimizer against 79 products5 mg per serving; the middle half of products list 15 mg to 33.85 mg, the median 30 mg.5 mg

84% of 79 products listing glucoraphanin give more (median 30 mg).

Source: NIH ODS Dietary Supplement Label Database, label 243364 (entered March 25, 2021), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Liver Optimizer's, rare ingredients counting for more.

  • Liver DetoxDivine Health 4 shared, 40% alike
  • Liver PFJarrow Formulas · off the market 7 shared, 36% alike
  • DetoxAccomplix · off the market 4 shared, 35% alike

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Usage: Take 3 tablets per day, preferably 1 with each meal or as directed by your qualified healthcare professional.
Warnings
Note: If you have a medical condition (especially diabetes or being treated for glucose control), are pregnant, lactating, trying to conceive, under the age of 18, or taking medications (especially for glucose control), consult your healthcare professional before using this product.
Keep out of the reach of children.
Allergens and what it does not contain
No wheat, gluten, soybeans, dairy, egg, fish/shellfish, or peanuts/tree nuts.
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 243364.

What else is on the label?

Other ingredients: Cellulose, Calcium Phosphate, Stearic Acid, Silicon Dioxide, Magnesium Stearate, food-grade Coating.

How many labels does Liver Optimizer have?

6 labels are on file under this name since January 24, 2014: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 243364 (current) Entered March 25, 2021 · off the market January 4, 2024 · 90 tablets · UPC 7 90011 29012 4
  2. Label 212204 Entered January 25, 2020 · off the market January 4, 2024 · 90 tablets · UPC 7 90011 29012 4
  3. Label 201216 Entered April 25, 2019 · off the market October 23, 2019 · 90 tablets · UPC 7 90011 29012 4
  4. Label 50840 Entered September 25, 2015 · off the market February 13, 2019 · 90 tablets · UPC 7 90011 29012 4
  5. Label 37551 Entered October 10, 2014 · off the market November 4, 2014 · 90 tablets · UPC 7 90011 29012 4
  6. Label 29868 Entered January 24, 2014 · off the market September 4, 2014 · 90 tablets · UPC 7 90011 29012 4

DSLD also links this label to: Liver PF (image difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Jarrow Formulas Superior Nutrition and Formulation (distributor), Los Angeles, CA. All Jarrow Formulas products.

Where next?