PlainVitamins

Liver Optima

by NutraKey · capsule · 90 capsules

  • On the market (NIH)
  • UPC 4 56355 73413 6
  • DSLD label 287416
  • Serving 3 capsules
  • 30 servings

Liver Optima by NutraKey lists 13 ingredients, 13 with an amount per serving of 3 capsules, such as 500 mg of milk thistle seed extract, 100 mg of N-acetyl cysteine, 100 mg of L-glutathione and 100 mg of bupleurum root concentrate. Its current label entered the NIH Dietary Supplement Label Database on June 22, 2023.

What is in Liver Optima?

Each row as the label prints it, per serving of 3 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Liver Optima: Supplement Facts rows against the market (DSLD label 287416, January 2026 release)
IngredientAmount% DVAmong products listing it
Milk Thistle Seed Extractas Silymarin80% silymarin500 mgMilk Thistle in Liver Optima against 1,277 products500 mg per serving; the middle half of products list 90 mg to 300 mg, the median 175 mg.500 mg

Higher than 87% of 1,277 products listing milk thistle (median 175 mg).

N-Acetyl Cysteine100 mgN-Acetyl Cysteine in Liver Optima against 1,259 products100 mg per serving; the middle half of products list 55 mg to 500 mg, the median 150 mg.100 mg

57% of 1,259 products listing N-acetyl cysteine give more (median 150 mg).

L-Glutathionefree-form100 mgGlutathione in Liver Optima against 717 products100 mg per serving; the middle half of products list 10 mg to 200 mg, the median 50 mg.100 mg

Higher than 61% of 717 products listing glutathione (median 50 mg).

Bupleurum Root Concentrate4:1 Concentrate100 mg
Grapeseed extractas Polyphenolsmin. 80% Polyphenols100 mgGrape in Liver Optima against 1,900 products100 mg per serving; the middle half of products list 25 mg to 100 mg, the median 50 mg.100 mg

Higher than 58% of 1,900 products listing grape (median 50 mg).

Dandelion Root Concentrate4:1100 mgDandelion in Liver Optima against 793 products100 mg per serving; the middle half of products list 50 mg to 250 mg, the median 100 mg.100 mg

48% of 793 products listing dandelion give more (median 100 mg).

Acetyl-L-Carnitine100 mgAcetyl L-Carnitine in Liver Optima against 933 products100 mg per serving; the middle half of products list 200 mg to 525 mg, the median 500 mg.100 mg

80% of 933 products listing acetyl L-carnitine give more (median 500 mg).

Scute Root Concentrate4:150 mgBaikal Skullcap in Liver Optima against 114 products50 mg per serving; the middle half of products list 40 mg to 200 mg, the median 90 mg.50 mg

54% of 114 products listing baikal skullcap give more (median 90 mg).

Pueraria Root Concentrateas Pueraria thomsonii4:150 mgKudzu in Liver Optima against 105 products50 mg per serving; the middle half of products list 43.75 mg to 500 mg, the median 100 mg.50 mg

67% of 105 products listing kudzu give more (median 100 mg).

Schisandra50 mgSchisandra in Liver Optima against 460 products50 mg per serving; the middle half of products list 50 mg to 240 mg, the median 108.75 mg.50 mg

73% of 460 products listing schisandra give more (median 108.75 mg).

Barberry30 mgBarberry in Liver Optima against 138 products30 mg per serving; the middle half of products list 30 mg to 200 mg, the median 75 mg.30 mg

70% of 138 products listing barberry give more (median 75 mg).

Turmeric30 mgTurmeric in Liver Optima against 2,369 products30 mg per serving; the middle half of products list 50 mg to 500 mg, the median 150 mg.30 mg

84% of 2,369 products listing turmeric give more (median 150 mg).

L-Methionine30 mgMETHIONINE in Liver Optima against 981 products30 mg per serving; the middle half of products list 25 mg to 250 mg, the median 100 mg.30 mg

71% of 981 products listing METHIONINE give more (median 100 mg).

Source: NIH ODS Dietary Supplement Label Database, label 287416 (entered June 22, 2023), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Liver Optima's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommended use: Take 1 serving (3 capsules) with water or your favorite beverage in the morning or mid-day before lunch. To maximize results, drink at least 64 ounces of water daily while using this product.
Warnings
Warning: Pregnant or lactating women, diabetics, hypoglycemics, and people with known medical conditions and/or taking drugs should consult with a licensed physician and/or pharmacist prior to taking dietary supplements.
Do not use if seal is broken.

Source: label statements in DSLD label 287416.

What else is on the label?

Other ingredients: Gelatin, Rice Flour.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Made in the USA.

How many labels does Liver Optima have?

One label is on file, entered on June 22, 2023.

  1. Label 287416 (current) Entered June 22, 2023 · on the market · 90 capsules · UPC 4 56355 73413 6

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Nutrakey (manufacturer), Longwood, FL. All NutraKey products.

Where next?