PlainVitamins

Liver Defend

by NuMedica · capsule · 60 vegetable capsules

  • On the market (NIH)
  • UPC 8 12527 01073 4
  • DSLD label 323565
  • Serving 1 capsule
  • 60 servings

Liver Defend by NuMedica lists 4 ingredients, 4 with an amount per serving of 1 capsule, such as 200 mcg of selenium, 262.5 mg of milk thistle seed extract, 250 mg of N-acetyl L-cysteine and 200 mg of alpha-lipoic acid. Its current label entered the NIH Dietary Supplement Label Database on January 23, 2025.

What is in Liver Defend?

Each row as the label prints it, per serving of 1 capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Liver Defend: Supplement Facts rows against the market (DSLD label 323565, January 2026 release)
IngredientAmount% DVAmong products listing it
Seleniumas Selenium Glycinate200 mcg364%Selenium in Liver Defend against 7,658 products200 mcg per serving; the middle half of products list 27 mcg to 100 mcg, the median 55 mcg.DV 55 mcgUL 400 mcg200 mcg

Higher than 82% of 7,658 products listing selenium (median 55 mcg).

Milk Thistle Seed Extractas Silybum marianum Seed Extract80% silymarin262.5 mgMilk Thistle in Liver Defend against 1,277 products262.5 mg per serving; the middle half of products list 90 mg to 300 mg, the median 175 mg.262.5 mg

Higher than 71% of 1,277 products listing milk thistle (median 175 mg).

N-Acetyl L-Cysteine250 mgN-Acetyl Cysteine in Liver Defend against 1,259 products250 mg per serving; the middle half of products list 55 mg to 500 mg, the median 150 mg.250 mg

Higher than 60% of 1,259 products listing N-acetyl cysteine (median 150 mg).

Alpha-Lipoic Acid200 mgAlpha Lipoic Acid in Liver Defend against 2,407 products200 mg per serving; the middle half of products list 25 mg to 150 mg, the median 50 mg.200 mg

Higher than 78% of 2,407 products listing alpha lipoic acid (median 50 mg).

Source: NIH ODS Dietary Supplement Label Database, label 323565 (entered January 23, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

2 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: Take one capsule once per day or as directed by your healthcare practitioner.
Warnings
Caution: Keep out of reach of children.
Allergens and what it does not contain
Does not contain: Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy.
Sourced from non-GMO ingredients. Gluten-Free
Storage
Storage: Keep tightly closed in a cool, dry place.

Source: label statements in DSLD label 323565.

What else is on the label?

Other ingredients: Hydroxypropylmethylcellulose, Magnesium Stearate, Bamboo Silica.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): cGMP Third-Party Certified Facility.

How many labels does Liver Defend have?

3 labels are on file under this name since August 31, 2018: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 323565 (current) Entered January 23, 2025 · on the market · 60 vegetable capsules · UPC 8 12527 01073 4
  2. Label 213568 Entered January 25, 2020 · off the market May 30, 2023 · 60 vegetable capsules · UPC 8 12527 01073 4
  3. Label 179997 Entered August 31, 2018 · off the market November 5, 2019 · 60 vegetable capsules · UPC 8 12527 01073 4

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names NuMedica LLC (distributor), Tulsa, OK. All NuMedica products.

Where next?