Lean 40

by First Choice Supplements · capsule · 60 capsules

  • On the market (NIH)
  • DSLD label 326022
  • Serving 2 capsules
  • 30 servings

Lean 40 by First Choice Supplements lists 15 ingredients, 15 with an amount per serving of 2 capsules, such as 250 mg of caffeine anhydrous, 75 mg of vitamin B12, 40 mg of 1,3-dimethylamylamine and 25 mg of ephedra vulgaris. Its current label entered the NIH Dietary Supplement Label Database on January 23, 2025.

What is in Lean 40?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Lean 40: Supplement Facts rows against the market (DSLD label 326022, January 2026 release)
IngredientAmount% DVAmong products listing it
Caffeine Anhydrous250 mgCaffeine in Lean 40 against 3,358 products250 mg per serving; the middle half of products list 100 mg to 275 mg, the median 200 mg.250 mg

Higher than 69% of 3,358 products listing caffeine (median 200 mg).

Vitamin B12as Cyanocobalamin1%75 mg3,125,000%*

This amount is far outside what other labels list for vitamin B12, or disagrees with the label's own %DV: possibly a unit or transcription slip in the database. Check the label image on DSLD.

1,3-Dimethylamylamine40 mg
Ephedra vulgaris25 mg
Grains of Paradise50 mgGrains of Paradise in Lean 40 against 163 products50 mg per serving; the middle half of products list 20 mg to 50 mg, the median 40 mg.50 mg

Higher than 67% of 163 products listing grains of paradise (median 40 mg).

Cocoa Seed Extract25 mgCocoa in Lean 40 against 255 products25 mg per serving; the middle half of products list 50 mg to 450 mg, the median 150 mg.25 mg

85% of 255 products listing cocoa give more (median 150 mg).

Theobroma grandiflorumas Octopamine25 mg
Noopept10 mgN-phenylacetyl-L-Prolylglycine ethyl ester in Lean 40 against 31 products10 mg per serving; the middle half of products list 5 mg to 20 mg, the median 15 mg.10 mg

52% of 31 products listing N-phenylacetyl-L-prolylglycine ethyl ester give more (median 15 mg).

Synephrine33 mgSynephrine in Lean 40 against 129 products33 mg per serving; the middle half of products list 20 mg to 40 mg, the median 25 mg.33 mg

Higher than 70% of 129 products listing synephrine (median 25 mg).

Gamma Butyrobetaine Ethyl Ester Hcl15 mgGamma butyrobetaine in Lean 40 against 91 products15 mg per serving; the middle half of products list 20 mg to 40 mg, the median 25 mg.15 mg

78% of 91 products listing gamma butyrobetaine give more (median 25 mg).

N-Acetyl-L-Tyrosine50 mgAcetyl L-Tyrosine in Lean 40 against 73 products50 mg per serving; the middle half of products list 200 mg to 600 mg, the median 300 mg.50 mg

93% of 73 products listing acetyl L-tyrosine give more (median 300 mg).

Ghost Pepper extract11 mg
Piperine10 mgPiperine in Lean 40 against 203 products10 mg per serving; the middle half of products list 4.75 mg to 10 mg, the median 5 mg.10 mg

Higher than 71% of 203 products listing piperine (median 5 mg).

Niacin10 mg63%*Niacin in Lean 40 against 12,413 products10 mg per serving; the middle half of products list 13.2 mg to 48 mg, the median 20 mg.DV 16 mgUL 35 mg10 mg

77% of 12,413 products listing niacin give more (median 20 mg).

Alpha Yohimbine2 mgRauwolscine in Lean 40 against 86 products2 mg per serving; the middle half of products list 1 mg to 2 mg, the median 1.75 mg.2 mg

Higher than 50% of 86 products listing rauwolscine (median 1.75 mg).

3,5-Diiodo-L-Thyronine200 mcg

* % Daily Value computed from the printed amount and the FDA Daily Value (21 CFR 101.9); the label prints none for that row.

Source: NIH ODS Dietary Supplement Label Database, label 326022 (entered January 23, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 78% of the 91 products that print an amount of gamma butyrobetaine list more than its 15 mg of gamma butyrobetaine (median 25 mg).
  • 93% of the 73 products that print an amount of acetyl L-tyrosine list more than its 50 mg of N-acetyl-L-tyrosine (filed by NIH under acetyl L-tyrosine) (median 300 mg).

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

How many labels does Lean 40 have?

One label is on file, entered on January 23, 2025.

  1. Label 326022 (current) Entered January 23, 2025 · on the market · 60 capsules

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names First Choice Supplements (manufacturer). All First Choice Supplements products.

Where next?