L-5-Mthf

by Adaptogen Research · capsule · 120 vegetarian capsules

  • On the market (NIH)
  • UPC 0 612524 953689
  • DSLD label 247064
  • Serving 1 capsule
  • 120 servings

L-5-Mthf by Adaptogen Research lists 2 ingredients, 2 with an amount per serving of 1 capsule, such as 1,000 mcg of folate. Its current label entered the NIH Dietary Supplement Label Database on April 22, 2021.

What is in L-5-Mthf?

Each row as the label prints it, per serving of 1 capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

L-5-Mthf: Supplement Facts rows against the market (DSLD label 247064, January 2026 release)
IngredientAmount% DVAmong products listing it
Folate1,000 mcg250%Folate in L-5-MTHF against 7,022 products1,000 mcg per serving; the middle half of products list 200 mcg to 400 mcg, the median 400 mcg.1,000 mcg

Higher than 93% of 7,022 products listing folate (median 400 mcg).

Quatrefolic (6S)-5-Methyltetrahydrofolate Glucosamine Salt2,000 mcg5-methyltetrahydrofolate glucosamine in L-5-MTHF against 176 products2,000 mcg per serving; the middle half of products list 300 mcg to 800 mcg, the median 593 mcg.2,000 mcg

Higher than 91% of 176 products listing 5-methyltetrahydrofolate glucosamine (median 593 mcg).

Source: NIH ODS Dietary Supplement Label Database, label 247064 (entered April 22, 2021), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • Its 1,000 mcg of folate is higher than 93% of the 7,022 folate products that print an amount; 183 list more.
  • Its 2,000 mcg of quatrefolic (6S)-5-methyltetrahydrofolate glucosamine salt (filed by NIH under 5-methyltetrahydrofolate glucosamine) is higher than 91% of the 176 5-methyltetrahydrofolate glucosamine products that print an amount; 13 list more.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommended Use: As a dietary supplement, take one capsule per day, or as directed by your health care practitioner.
Warnings
Report any adverse reactions to 302-213-0030
Keep out of reach of children.
Allergens and what it does not contain
Made with Non-GMO ingredients Does not contain gluten
Storage
Store at room temperature.

Source: label statements in DSLD label 247064.

What else is on the label?

Other ingredients: Spinach juice powder, Microcrystalline Cellulose, Cellulose, L-Leucine.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Guaranteed GMP Compliant Products.

How many labels does L-5-Mthf have?

One label is on file, entered on April 22, 2021.

  1. Label 247064 (current) Entered April 22, 2021 · on the market · 120 vegetarian capsules · UPC 0 612524 953689

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Adaptogen Research (distributor), Newark, DE. All Adaptogen Research products.

Where next?