Joint Mediator

by Pure Encapsulations · capsule · 180 capsules

  • On the market (NIH)
  • UPC 7 66298 01258 2
  • DSLD label 182967
  • Serving 3 capsules
  • 60 servings

Joint Mediator by Pure Encapsulations lists 6 ingredients, 2 with an amount per serving of 3 capsules, such as 15 mcg (600 IU) of vitamin D and 750 mg of glucosamine sulfate; 1 gives its count of live cultures or enzyme activity instead of a weight; 3 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on January 7, 2019.

What is in Joint Mediator?

Each row as the label prints it, per serving of 3 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Joint Mediator: Supplement Facts rows against the market (DSLD label 182967, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin Das Cholecalciferol, Vitamin D3Vitamin D (Form: as Cholecalciferol (Alt. Name: D3)) Note: 600 IU15 mcg (600 IU)75%Vitamin D in Joint Mediator against 14,175 products15 mcg per serving; the middle half of products list 10 mcg to 25 mcg, the median 15 mcg.DV 20 mcgUL 100 mcg15 mcg

51% of 14,175 products listing vitamin D give more (median 15 mcg). Per day at the most servings: 30 mcg.

Glucosamine Sulfateas Crab, ShrimpGlucosamine Sulfate (Form: from Crab, Shrimp)750 mgGlucosamine Sulfate in Joint Mediator against 875 products0.75 g per serving; the middle half of products list 0.5 g to 1.5 g, the median 1 g.0.75 g

53% of 875 products listing glucosamine sulfate give more (median 1 g). Per day at the most servings: 1.5 g.

Proprietary BlendProprietary Blend Note: providing910 mg
Indian Frankincense (Boswellia serrata) extractas Boswellic AcidsIndian Frankincense (Boswellia serrata) extract (Form: standardized to contain 70% Boswellic Acids) PlantPart: gum resin Genus: Boswellia Species: serratain the blend, no amount given
Turmeric (Curcuma longa) extractas CurcuminoidsTurmeric (Curcuma longa) extract (Form: standardized to contain 95% Curcuminoids) PlantPart: root Genus: Curcuma Species: longain the blend, no amount given
L-GlutamineL-Glutamine Note: free-formin the blend, no amount given
BromelainBromelain Note: 2,400 GDU/gram

Source: NIH ODS Dietary Supplement Label Database, label 182967 (entered January 7, 2019), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient; 4 ingredients sit inside a blend, so their amounts cannot be compared.

The NIH database records 1 to 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Joint Mediator's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommendations: As a dietary supplement, take 3 capsules in the morning and 3 capsules in the evening, with meals, with 8-10 oz water.
Warnings
Warning: Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use.
Do not take if you are sensitive to shellfish.
Keep out of the reach of children.
Use only if safety seal is intact.
Contains shellfish (crab, shrimp)
Allergens and what it does not contain
Certified Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org
Gluten-free & Non-GMO
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 182967.

What else is on the label?

Other ingredients: Vegetarian Capsule, Ascorbyl Palmitate.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): GF. Listed with: Certified gluten-free (GFCO) (a seal is the label's claim; the certifier's own list confirms it).

How many labels does Joint Mediator have?

2 labels are on file under this name since January 7, 2019: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 219150 Entered April 23, 2020 · off the market October 23, 2018 · 180 capsules · UPC 7 66298 01258 2
  2. Label 182967 (current) Entered January 7, 2019 · on the market · 180 capsules · UPC 7 66298 01258 2

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Pure Encapsulations (manufacturer), Sudbury, MA. All Pure Encapsulations products.

Where next?