PlainVitamins

Joint Advance

by Advanced Nutrition Systems · capsule · 60 liquid capsules

  • On the market (NIH)
  • UPC 8 14995 02069 7
  • DSLD label 180578
  • Serving 2 capsules
  • 30 servings

Joint Advance by Advanced Nutrition Systems lists 9 ingredients, 9 with an amount per serving of 2 capsules, such as 25 mcg (1,000 IU) of vitamin D3, 40 mg of UC-II standardized cartilage, 1,000 mg of fish oil and 200 mg of turmeric (curcuma longa) extract. Its current label entered the NIH Dietary Supplement Label Database on August 31, 2018.

What is in Joint Advance?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Joint Advance: Supplement Facts rows against the market (DSLD label 180578, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin D3as Cholecalciferol25 mcg (1,000 IU)125%Vitamin D in Joint Advance against 14,175 products25 mcg per serving; the middle half of products list 10 mcg to 25 mcg, the median 15 mcg.DV 20 mcgUL 100 mcg25 mcg

Higher than 59% of 14,175 products listing vitamin D (median 15 mcg).

UC-II standardized Cartilageas Collagen40 mgCartilage in Joint Advance against 199 products40 mg per serving; the middle half of products list 40 mg to 750 mg, the median 100 mg.40 mg

57% of 199 products listing cartilage give more (median 100 mg).

Total Collagen10 mgCollagen in Joint Advance against 1,008 products0.01 g per serving; the middle half of products list 0.1 g to 4.2 g, the median 1 g.0.01 g

90% of 1,008 products listing collagen give more (median 1 g).

Fish Oil1,000 mgFish Oil in Joint Advance against 1,990 products1 g per serving; the middle half of products list 1 g to 2 g, the median 1.2 g.1 g

55% of 1,990 products listing fish oil give more (median 1.2 g).

Eicosapentaenoic Acid400 mgEPA (Eicosapentaenoic Acid) in Joint Advance against 3,134 products400 mg per serving; the middle half of products list 120 mg to 590 mg, the median 300 mg.400 mg

Higher than 63% of 3,134 products listing EPA (eicosapentaenoic acid) (median 300 mg).

Docosahexaenoic Acid200 mgDHA in Joint Advance against 3,627 products200 mg per serving; the middle half of products list 104 mg to 400 mg, the median 232 mg.200 mg

54% of 3,627 products listing DHA give more (median 232 mg).

Turmeric (Curcuma longa) extractas Curcumin, Tumerones, Turmeric CO2 extractTurmeric (Curcuma longa) extract (Form: 95% Curcumin, and Turmeric CO2 extract PlantPart: root, 48% Tumerones) PlantPart: root Genus: Curcuma Species: longa200 mgTurmeric in Joint Advance against 2,369 products200 mg per serving; the middle half of products list 50 mg to 500 mg, the median 150 mg.200 mg

Higher than 51% of 2,369 products listing turmeric (median 150 mg).

White Willow (Salix alba) extractas SalicinWhite Willow (Salix alba) extract (Form: 25% Salicin) PlantPart: bark Genus: Salix Species: alba150 mgWhite Willow in Joint Advance against 256 products150 mg per serving; the middle half of products list 80 mg to 400 mg, the median 150 mg.150 mg

48% of 256 products listing white willow give more (median 150 mg).

Bioperine Black Pepper (Piper nigrum) extractas PiperineBioperine Black Pepper (Piper nigrum) extract (Form: 95% Piperine) PlantPart: fruit Genus: Piper Species: nigrum5 mgBlack Pepper in Joint Advance against 2,363 products5 mg per serving; the middle half of products list 5 mg to 10 mg, the median 5 mg.5 mg

33% of 2,363 products listing black pepper give more (median 5 mg).

Source: NIH ODS Dietary Supplement Label Database, label 180578 (entered August 31, 2018), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 57% of the 199 products that print an amount of cartilage list more than its 40 mg of UC-II standardized cartilage (filed by NIH under cartilage) (median 100 mg).
  • 90% of the 1,008 products that print an amount of collagen list more than its 0.01 g of total collagen (filed by NIH under collagen) (median 1 g).

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Joint Advance's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Use: As a dietary supplement, adults take 1 serving (2 Capsules) in the morning with a meal. Please read the entire label before use.
Warnings
Contains: Soy, Fish (sardines, anchovies and mackerel)
Produced in a facility that also uses milk, eggs, fish, shellfish, peanuts, tree nuts, wheat and soy.
Warning: This product is intended for use by healthy adults over the age of 18. Not intended for use by those with a medical condition. Use only as directed. Do not exceed recommended daily intake.
Consult a physician or licensed qualified health care professional prior to use if you are taking medication, or if you have a medical condition. Do not use if pregnant, nursing or allergic or contraindicated to aspirin. If you are taking aspirin or blood thinning or other medication, consult your physician before using this product.
Do not use if pregnant, nursing or allergic or contraindicated to aspirin.
Discontinue use 2 weeks prior to surgery or if stomach upset occurs. Do not use if safety seal under cap is broken.
Keep out of reach of children.
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 180578.

What else is on the label?

Other ingredients: Gelatin, Sugar, Talc, Starch, Pharmaceutical Glaze, Povidone, Silicon Dioxide, Titanium Dioxide, Mixed Tocopherols, FD&C Yellow #5 Lake, FD&C Yellow #6 Lake.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): UC II BioPerine; cGMP Good Manufacturing Practice Quality Product Made in the USA.

How many labels does Joint Advance have?

One label is on file, entered on August 31, 2018.

  1. Label 180578 (current) Entered August 31, 2018 · on the market · 60 liquid capsules · UPC 8 14995 02069 7

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Advanced Nutrition LLC (distributor), Denver, CO. All Advanced Nutrition Systems products.

Where next?