PlainVitamins

Joint-4

by Xendurance · capsule · 90 capsules

  • On the market (NIH)
  • UPC 8 55532 00271 4
  • DSLD label 243998
  • Serving 3 capsules

Joint-4 by Xendurance lists 4 ingredients, 4 with an amount per serving of 3 capsules, such as 750 mg of glucosamine HCl, 600 mg of chondroitin sulfate, 300 mg of boswellia serrata extract and 750 mg of methylsulfonylmethane. Its current label entered the NIH Dietary Supplement Label Database on February 25, 2021.

What is in Joint-4?

Each row as the label prints it, per serving of 3 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Joint-4: Supplement Facts rows against the market (DSLD label 243998, January 2026 release)
IngredientAmount% DVAmong products listing it
Glucosamine HCl750 mgGlucosamine Hydrochloride in Joint-4 against 628 products0.75 g per serving; the middle half of products list 0.75 g to 1.5 g, the median 1.5 g.0.75 g

68% of 628 products listing glucosamine hydrochloride give more (median 1.5 g).

Chondroitin Sulfate600 mgChondroitin Sulfate in Joint-4 against 950 products600 mg per serving; the middle half of products list 200 mg to 1,200 mg, the median 400 mg.600 mg

Higher than 58% of 950 products listing chondroitin sulfate (median 400 mg).

Boswellia serrata extract300 mgBoswellia in Joint-4 against 665 products300 mg per serving; the middle half of products list 100 mg to 290 mg, the median 135 mg.300 mg

Higher than 75% of 665 products listing boswellia (median 135 mg).

Methylsulfonylmethane750 mgMethylsulfonylmethane in Joint-4 against 1,454 products750 mg per serving; the middle half of products list 150 mg to 1,000 mg, the median 500 mg.750 mg

Higher than 66% of 1,454 products listing methylsulfonylmethane (median 500 mg).

Source: NIH ODS Dietary Supplement Label Database, label 243998 (entered February 25, 2021), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Joint-4's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Optimal directions/First 30 days 3 capsules twice a day 3 capsules with morning meal + 3 capsules with evening meal Optimal directions/After 30 days 3 capsules Once a day with meal If joint discomfort increases at lower dosages, increase dosage to 3 capsules-2 times per day.
Warnings
Warning: Do not use if pregnant, nursing or under the age of 18.
Warning: Do not use if pregnant, nursing or under the age of 18. Consult with a doctor before taking this or any other dietary supplement, especially if you have or suspect you may have a medical condition, including but not limited to diabetes or hypoglycemia, or are taking any over the counter products.
Use only as directed. Immediately discontinue use and consult your doctor if any adverse reactions occur.
Keep out of reach of children.
Do not use if package is open.
Contains: Shellfish
Allergens and what it does not contain
Guarantee: No added sugar, salt, wheat, yeast or dairy products. No artificial preservatives, colors or flavors.
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 243998.

What else is on the label?

Other ingredients: Gelatin, Magnesium Stearate.

How many labels does Joint-4 have?

One label is on file, entered on February 25, 2021.

  1. Label 243998 (current) Entered February 25, 2021 · on the market · 90 capsules · UPC 8 55532 00271 4

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Lifespan International US, LLC. (distributor), Carefree, AZ. All Xendurance products.

Where next?