PlainVitamins

Immune Defense

by Safrel · capsule · 60 capsules

  • On the market (NIH)
  • UPC 8 50012 52081 8
  • DSLD label 318395
  • Serving 2 capsules
  • 30 servings

Immune Defense by Safrel lists 4 ingredients, 4 with an amount per serving of 2 capsules, such as 500 mg of quercetin, 100 mg of zinc, 1,000 mg of vitamin C and 1,500 IU (37.5 mcg) of vitamin D3. Its current label entered the NIH Dietary Supplement Label Database on September 25, 2024.

What is in Immune Defense?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Immune Defense: Supplement Facts rows against the market (DSLD label 318395, January 2026 release)
IngredientAmount% DVAmong products listing it
Quercetin500 mgQuercetin in Immune Defense against 1,548 products500 mg per serving; the middle half of products list 26.5 mg to 250 mg, the median 100 mg.500 mg

Higher than 84% of 1,548 products listing quercetin (median 100 mg).

Zincas Zinc Picolinate100 mg657%Zinc in Immune Defense against 13,186 products100 mg per serving; the middle half of products list 5 mg to 15 mg, the median 11 mg.DV 11 mgUL 40 mg100 mg

Higher than over 99% of 13,186 products listing zinc (median 11 mg). 2.5 times the adult UL a day.

Vitamin Cas Ascorbic Acid1,000 mg1,667%Vitamin C in Immune Defense against 18,583 products1,000 mg per serving; the middle half of products list 60 mg to 270 mg, the median 100 mg.DV 90 mgUL 2,000 mg1,000 mg

Higher than 91% of 18,583 products listing vitamin C (median 100 mg).

Vitamin D3as Cholecalciferol1,500 IU (37.5 mcg)375%Vitamin D in Immune Defense against 14,175 products37.5 mcg per serving; the middle half of products list 10 mcg to 25 mcg, the median 15 mcg.DV 20 mcgUL 100 mcg37.5 mcg

Higher than 78% of 14,175 products listing vitamin D (median 15 mcg).

Source: NIH ODS Dietary Supplement Label Database, label 318395 (entered September 25, 2024), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • At 1 serving a day, the most its directions give, the label lists 100 mg of zinc, 2.5 times the adult Tolerable Upper Intake Level.
  • Its 1,000 mg of vitamin C is higher than 91% of the 18,583 vitamin C products that print an amount; 445 list more.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Immune Defense's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Use As a dietary supplement, take one (1) tablet daily preferrably with a meal or as directed by a healthcare professional.
Directions: Take one (2) capsules daily preferrably with a meal or as directed by a healthcare professional.
Warnings
Caution Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.
Stop use and contact a physician if adverse reactions occur. Do not use if seal under cap is broken or missing
Allergens and what it does not contain
No: Milk, egg, fish, crustacean shellfish, tree nuts, peanuts, yeast, artificial colors, flavors or preservatives.
Storage
Storage Store at room temperature 59 Degrees - 86 Degrees F (15 Degrees - 30 Degrees C). Keep bottle tightly closed.

Source: label statements in DSLD label 318395.

What else is on the label?

Other ingredients: Cellulose, Magnesium Stearate, Silicon Dioxide.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Made in the USA.

How many labels does Immune Defense have?

One label is on file, entered on September 25, 2024.

  1. Label 318395 (current) Entered September 25, 2024 · on the market · 60 capsules · UPC 8 50012 52081 8

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Safrel Pharmaceuticals (distributor), Bridgewater, NJ. All Safrel products.

Where next?