PlainVitamins

HPA Adapt

by Integrative Therapeutics · capsule · 120 capsules

  • On the market (NIH)
  • UPC 8 71791 10270 5
  • DSLD label 246428
  • Serving 2 to 4 capsules; amounts per 4 capsules
  • 30 servings

HPA Adapt by Integrative Therapeutics lists 5 ingredients, 5 with an amount per serving of 4 capsules, such as 400 mg of rhodiola (rhodiola rosea) root extract, 300 mg of ashwagandha (withania somnifera) (sensoril brand) root and leaf extract, 300 mg of eleuthero (eleutherococcus senticosus) root extract and 200 mg of holy basil (ocimum sanctum) leaf extract, beside 1 Nutrition Facts row (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on March 25, 2021.

What is in HPA Adapt?

Each row as the label prints it, per serving of 4 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

HPA Adapt: Supplement Facts rows against the market (DSLD label 246428, January 2026 release)
IngredientAmount% DVAmong products listing it
Total Carbohydratesless than 1 g1%
Rhodiola (Rhodiola rosea) root extractas Rosavins, SalidrosideRhodiola (Rhodiola rosea) root extract (Form: standardized to contain 3% Rosavins, and 1% Salidroside) PlantPart: root Genus: Rhodiola Species: rosea400 mgRhodiola in HPA Adapt against 945 products400 mg per serving; the middle half of products list 50 mg to 250 mg, the median 100 mg.400 mg

Higher than 88% of 945 products listing rhodiola (median 100 mg).

Ashwagandha (Withania somnifera) (Sensoril brand) root and leaf extract300 mgAshwagandha in HPA Adapt against 1,646 products300 mg per serving; the middle half of products list 125 mg to 500 mg, the median 250 mg.300 mg

Higher than 59% of 1,646 products listing ashwagandha (median 250 mg).

Eleuthero (Eleutherococcus senticosus) root extractas EleutherosidesEleuthero (Eleutherococcus senticosus) root extract (Form: standardized to contain 0.8% Eleutherosides) PlantPart: root Genus: Eleutherococcus Species: senticosus300 mgEleuthero in HPA Adapt against 726 products300 mg per serving; the middle half of products list 50 mg to 200 mg, the median 100 mg.300 mg

Higher than 84% of 726 products listing eleuthero (median 100 mg).

Holy Basil (Ocimum sanctum) leaf extractas Triterpenoic Acids, Oleanolic Acid, Ursolic AcidHoly Basil (Ocimum sanctum) leaf extract (Form: standardized to contain 2.5% Triterpenoic Acids, including Ursolic Acid, and Oleanolic Acid) PlantPart: leaf Genus: Ocimum Species: sanctum200 mgHoly Basil in HPA Adapt against 387 products200 mg per serving; the middle half of products list 50 mg to 400 mg, the median 129 mg.200 mg

Higher than 57% of 387 products listing holy basil (median 129 mg).

MacaPure brand Maca (Lepidium meyenii) root extractas Macaenes, MacamidesMacaPure brand Maca (Lepidium meyenii) root extract (Form: standardized to contain 0.6% Macaenes, and 0.6% Macamides) PlantPart: root Genus: Lepidium Species: meyenii150 mgMaca in HPA Adapt against 728 products150 mg per serving; the middle half of products list 118.13 mg to 600 mg, the median 250 mg.150 mg

70% of 728 products listing maca give more (median 250 mg).

Source: NIH ODS Dietary Supplement Label Database, label 246428 (entered March 25, 2021), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with HPA Adapt's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommendation: Adults take 2 to 4 capsules daily on an empty stomach, or as recommended by your healthcare professional. For best results take in the morning and at mid-day.
Warnings
Warning: Do not use if you are pregnant or under 18 years of age.
Do not use if you are pregnant or under 18 years of age. If you are nursing, diabetic, or taking any prescription drugs, consult your healthcare professional prior to use.
Keep out of reach of children.
Safety sealed with inner seal. Do not use if seal is broken or missing.
Allergens and what it does not contain
Contains no salt, wheat, gluten, soy, dairy products, ingredients of animal origin, or artificial colors, or flavors.
Storage
Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.

Source: label statements in DSLD label 246428.

What else is on the label?

Other ingredients: Hydroxypropyl Methylcellulose, Ascorbyl Palmitate, Cellulose, Silicon Dioxide.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Quality Global Sourcing Bottled & Tested In The USA.

How many labels does HPA Adapt have?

4 labels are on file under this name since September 22, 2016: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 246428 (current) Entered March 25, 2021 · on the market · 120 capsules · UPC 8 71791 10270 5
  2. Label 223244 Entered June 24, 2020 · off the market February 2, 2021 · 120 veg capsules · UPC 8 71791 10270 5
  3. Label 76935 Entered September 21, 2017 · off the market January 15, 2020 · 120 veg capsules · UPC 8 71791 10270 5
  4. Label 64794 Entered September 22, 2016 · off the market June 21, 2017 · 120 veg capsules · UPC 8 71791 10270 5

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Integrative Therapeutics, LLC (manufacturer), Green Bay, WI. All Integrative Therapeutics products.

Where next?