PlainVitamins

Homocysteine Modulators

by Solgar · capsule · 120 vegetable capsules

  • On the market (NIH)
  • UPC 0 33984 01411 4
  • DSLD label 218309
  • Serving 2 vegetarian capsules
  • 60 servings

Homocysteine Modulators by Solgar lists 6 ingredients, 6 with an amount per serving of 2 vegetarian capsules, such as 50 mg of vitamin B6, 666 mcg DFE of folate, 500 mcg of vitamin B12 and 1,000 mg of trimethylglycine. Its current label entered the NIH Dietary Supplement Label Database on April 23, 2020.

What is in Homocysteine Modulators?

Each row as the label prints it, per serving of 2 vegetarian capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Homocysteine Modulators: Supplement Facts rows against the market (DSLD label 218309, January 2026 release)
IngredientAmount% DVAmong products listing it
Calories5 Calories
Vitamin B6as Pyridoxine HydrochlorideVitamin B6 (Form: as Pyridoxine HCl)50 mg2,941%Vitamin B6 in Homocysteine Modulators against 15,277 products56 mg per serving; the middle half of products list 2 mg to 20 mg, the median 6 mg.DV 1.7 mgUL 100 mg56 mg

Higher than 94% of 15,277 products listing vitamin B6 (median 6 mg).

Folate666 mcg DFE167%
Folic Acid400 mcg
Vitamin B12as CyanocobalaminVitamin B12 (Form: as Cyanocobalamin)500 mcg20,833%Vitamin B12 in Homocysteine Modulators against 14,425 products500 mcg per serving; the middle half of products list 6 mcg to 200 mcg, the median 36 mcg.DV 2.4 mcg500 mcg

Higher than 82% of 14,425 products listing vitamin B12 (median 36 mcg).

TrimethylglycineTrimethylglycine (Alt. Name: TMG) Note: 1 g1,000 mgBetaine in Homocysteine Modulators against 731 products1,000 mg per serving; the middle half of products list 50 mg to 1,250 mg, the median 250 mg.1,000 mg

Higher than 68% of 731 products listing betaine (median 250 mg).

Pyridoxal 5-Phosphate6 mg

Source: NIH ODS Dietary Supplement Label Database, label 218309 (entered April 23, 2020), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • Its 56 mg of vitamin B6 (2 rows of the label added together) is higher than 94% of the 15,277 vitamin B6 products that print an amount; 949 list more.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Use: As a dietary supplement for adults, take two (2) vegetable capsules daily, preferably with a meal, or as directed by a healthcare practitioner.
Warnings
If you are pregnant, nursing, taking any medications or have any medical condition, please consult your healthcare practitioner before taking any dietary supplement.
Discontinue use and consult your healthcare practitioner if any adverse reactions occur.
Keep out of reach of children.
Do not use if outer bottle seal is missing or damaged.
Allergens and what it does not contain
Free of: Gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor and color.
Gluten, wheat & dairy free Non-GMO
Storage
Store at room temperature.

Source: label statements in DSLD label 218309.

What else is on the label?

Other ingredients: Vegetable Cellulose, Stearic Acid, Microcrystalline Cellulose, Vegetable Magnesium Stearate, PhytO2X Antioxidant Blend.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): GF Certified Gluten-free K Parve (Kosher). Listed with: Certified gluten-free (GFCO) (a seal is the label's claim; the certifier's own list confirms it).

How many labels does Homocysteine Modulators have?

7 labels are on file under this name since April 24, 2015: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 218309 (current) Entered April 23, 2020 · on the market · 120 vegetable capsules · UPC 0 33984 01411 4
  2. Label 218305 Entered April 23, 2020 · off the market November 2, 2022 · 60 vegetable capsules · UPC 0 33984 01410 7
  3. Label 81848 Entered December 22, 2017 · off the market September 28, 2016 · 120 vegetable capsules · UPC 0 33984 01411 4
  4. Label 81846 Entered December 22, 2017 · off the market September 28, 2016 · 60 vegetable capsules · UPC 0 33984 01410 7
  5. Label 65477 Entered October 22, 2016 · off the market November 18, 2019 · 120 vegetable capsules · UPC 0 33984 01411 4
  6. Label 65476 Entered October 22, 2016 · off the market November 18, 2019 · 60 vegetable capsules · UPC 0 33984 01410 7
  7. Label 44689 Entered April 24, 2015 · off the market September 9, 2016 · 60 vegetable capsules · UPC 0 33984 01410 7

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Solgar, Inc. (manufacturer), Leonia, NJ, U.S.A.. All Solgar products.

Where next?