PlainVitamins

Homocysteine Defense

by Source Naturals · tablet or pill · 120 tablets

  • On the market (NIH)
  • UPC 0 21078 01039 5
  • DSLD label 273056
  • Serving 2 tablets
  • 60 servings

Homocysteine Defense by Source Naturals lists 6 ingredients, 6 with an amount per serving of 2 tablets, such as 50 mg of vitamin B6, 1,360 mcg DFE of folate, 500 mcg of vitamin B12 and 90 mg of calcium, beside 1 Nutrition Facts row (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on August 23, 2022.

What is in Homocysteine Defense?

Each row as the label prints it, per serving of 2 tablets. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Homocysteine Defense: Supplement Facts rows against the market (DSLD label 273056, January 2026 release)
IngredientAmount% DVAmong products listing it
Calories5 Calories
Protein1 g2%Protein in Homocysteine Defense against 8,985 products1 g per serving; the middle half of products list 2 g to 24 g, the median 16 g.1 g

77% of 8,985 products listing protein give more (median 16 g).

Vitamin B6as Pyridoxine HydrochlorideVitamin B-6 (Form: as Pyridoxine HCl)50 mg2,941%Vitamin B6 in Homocysteine Defense against 15,277 products50 mg per serving; the middle half of products list 2 mg to 20 mg, the median 6 mg.DV 1.7 mgUL 100 mg50 mg

Higher than 87% of 15,277 products listing vitamin B6 (median 6 mg).

Folate1,360 mcg DFE340%
Folic Acid800 mcg
Vitamin B12as Cyanocobalamin500 mcg20,833%Vitamin B12 in Homocysteine Defense against 14,425 products500 mcg per serving; the middle half of products list 6 mcg to 200 mcg, the median 36 mcg.DV 2.4 mcg500 mcg

Higher than 82% of 14,425 products listing vitamin B12 (median 36 mcg).

Calciumas Dibasic Calcium Phosphate90 mg7%Calcium in Homocysteine Defense against 17,831 products90 mg per serving; the middle half of products list 50 mg to 252 mg, the median 115 mg.DV 1,300 mgUL 2,500 mg90 mg

60% of 17,831 products listing calcium give more (median 115 mg).

Trimethylglycine1 gBetaine in Homocysteine Defense against 731 products1,000 mg per serving; the middle half of products list 50 mg to 1,250 mg, the median 250 mg.1,000 mg

Higher than 68% of 731 products listing betaine (median 250 mg).

Source: NIH ODS Dietary Supplement Label Database, label 273056 (entered August 23, 2022), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Homocysteine Defense's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Use: 2 tablets daily.
Warnings
Note: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.
Do not use if either tamper-evident seal is broken or missing.
Keep out of the reach of children.
Allergens and what it does not contain
Contains no yeast, dairy, egg, gluten, corn, soy or wheat. Contains no starch, preservatives, or artificial color, flavor or fragrance.
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 273056.

What else is on the label?

Other ingredients: Dibasic Calcium Phosphate, Stearic Acid, modified Cellulose Gum, Silica, Magnesium Stearate.

How many labels does Homocysteine Defense have?

2 labels are on file under this name since April 25, 2017: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 273056 (current) Entered August 23, 2022 · on the market · 120 tablets · UPC 0 21078 01039 5
  2. Label 72845 Entered April 25, 2017 · off the market December 22, 2021 · 120 tablets · UPC 0 21078 01039 5

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Source Naturals, Inc. (distributor), Santa Cruz, CA. All Source Naturals products.

Where next?