HoloZyme
by Healthy Gut · capsule · 180 capsules
- On the market (NIH)
- UPC 8 60007 20580 4
- DSLD label 336616
- Serving 2 capsules
- 90 servings
HoloZyme by Healthy Gut lists 14 ingredients; 6 give their count of live cultures or enzyme activity instead of a weight; 8 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on August 22, 2025.
What is in HoloZyme?
Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).
| Ingredient | Amount | % DV | Among products listing it |
|---|---|---|---|
| Activ-Blend | 656 mg | ||
| Protease | 120,000 HUT | ||
| Amylase | 22,000 SKB | ||
| Lipase | 700 FIP | ||
| Cellulase | 1,000 CU | ||
| Sucrase | 400 SU | ||
| Alpha-Galactosidase650 GALU | in the blend, no amount given | ||
| Lactase800 LACU | in the blend, no amount given | ||
| Maltase300 DP | in the blend, no amount given | ||
| Xylanase | 5,000 XU | ||
| Phytase20 FTU | in the blend, no amount given | ||
| Patented AES Absorption System | 290 mg | ||
| Calcium Ascorbate | in the blend, no amount given | The label names the compound (Calcium Ascorbate); its amount is likely the compound's weight, not the calcium it holds, so it is not placed among other products. | |
| Magnesium Citrate | in the blend, no amount given | The label names the compound (Magnesium Citrate); its amount is likely the compound's weight, not the magnesium it holds, so it is not placed among other products. | |
| HaloCarbon Black Mineral Complex | in the blend, no amount given | ||
| Zinc Gluconate | in the blend, no amount given | The label names the compound (Zinc Gluconate); its amount is likely the compound's weight, not the zinc it holds, so it is not placed among other products. | |
| Manganese Gluconate | in the blend, no amount given | The label names the compound (Manganese Gluconate); its amount is likely the compound's weight, not the manganese it holds, so it is not placed among other products. |
Source: NIH ODS Dietary Supplement Label Database, label 336616 (entered August 22, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.
Is that a lot?
Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient; 14 ingredients sit inside a blend, so their amounts cannot be compared.
The NIH database records 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.
The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.
Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.
Which products have the closest formulas?
The products whose ingredient lists overlap most with HoloZyme's, rare ingredients counting for more.
- Total Systemic EnzymeNutraNomics · off the market 11 shared, 71% alike
- VegeZymeKaruna 9 shared, 69% alike
- Tyler SimilaseIntegrative Therapeutics · off the market 8 shared, 65% alike
- CompleteGest Vegetarian EnzymesEnzymatic Therapy · off the market 8 shared, 65% alike
- CompleteGestEnzymatic Therapy · off the market 8 shared, 65% alike
- Extrazyme-13LifeTIME 9 shared, 64% alike
Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.
What does the label say about taking it?
Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.
- Directions
- Suggested use: Two (2) capsules with each meal and two (2) capsules on an empty stomach.
- Warnings
- Caution: If pregnant or nursing, consult a physician before use.
- Keep out of the reach of children.
- Do not use if seal is broken.
- No added: This product does not contain milk, egg, fish, shellfish, soy, wheat, gluten, peanuts, tree nuts, yeast, rice, artificial colors or flavors, but is made in a facility that handles these allergens.
- Allergens and what it does not contain
- Non GMO No fillers
- Storage
- Storage: Keep tightly closed in a cool, dry place in the original container. Do not expose to excessive heat.
Source: label statements in DSLD label 336616.
What else is on the label?
Other ingredients: Hypromellose.
How many labels does HoloZyme have?
3 labels are on file under this name since April 23, 2024: other sizes, label designs and reformulations. The current one leads this page.
- Label 336616 (current) Entered August 22, 2025 · on the market · 180 capsules · UPC 8 60007 20580 4
- Label 315867 Entered October 24, 2024 · off the market April 30, 2025 · 180 capsules · UPC 8 60007 20580 4
- Label 308950 Entered April 23, 2024 · off the market March 26, 2024 · 180 capsules · UPC 8 60007 20580 4
Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).
Who makes it?
The label names Healthy Gut, LLC (distributor), Boulder, CO. All Healthy Gut products.