High Potency Protease

by Nature's Sunshine · capsule · 60 capsules

  • On the market (NIH)
  • UPC 0 99904 01876 1
  • DSLD label 278115
  • Serving 1 capsule
  • 60 servings

High Potency Protease by Nature's Sunshine lists 2 ingredients, 1 with an amount per serving of 1 capsule, such as 400 mg of protease; 1 sits inside a blend without its own amount. Its current label entered the NIH Dietary Supplement Label Database on October 24, 2022.

What is in High Potency Protease?

Each row as the label prints it, per serving of 1 capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

High Potency Protease: Supplement Facts rows against the market (DSLD label 278115, January 2026 release)
IngredientAmount% DVAmong products listing it
ProteaseProtease Note: 180,000 HUT400 mgProteolytic Enzymes (Proteases) in High Potency Protease against 327 products400 mg per serving; the middle half of products list 10 mg to 100 mg, the median 30 mg.400 mg

Higher than 93% of 327 products listing proteolytic enzymes (proteases) (median 30 mg). Per day at the most servings: 1,200 mg.

Proprietary Blend100 mg
Beet root Fiberin the blend, no amount given
Trace Mineral concentratein the blend, no amount given

Source: NIH ODS Dietary Supplement Label Database, label 278115 (entered October 24, 2022), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • Its 400 mg of proteolytic enzymes (proteases) is higher than 93% of the 327 proteolytic enzymes (proteases) products that print an amount; 21 list more.

The NIH database records 3 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

1 product lists the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommended Use: Take 1 capsule between meals up to three times daily.
Warnings
Do not use if inner seal is missing or damaged.

Source: label statements in DSLD label 278115.

What else is on the label?

Other ingredients: Capsule.

How many labels does High Potency Protease have?

3 labels are on file under this name since October 23, 2019: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 278115 (current) Entered October 24, 2022 · on the market · 60 capsules · UPC 0 99904 01876 1
  2. Label 277250 Entered September 22, 2022 · on the market · 60 capsules · UPC 0 99904 01876 1
  3. Label 207629 Entered October 23, 2019 · off the market January 21, 2022 · 60 capsules · UPC 0 99904 01876 1

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Nature's Sunshine Products, Inc. (manufacturer), Spanish Fork, UT. All Nature's Sunshine products.

Where next?