PlainVitamins

HepatoPlex

by Karuna · tablet or pill · 120 tablets

  • On the market (NIH)
  • DSLD label 24419
  • Serving 2 tablets
  • 60 servings

HepatoPlex by Karuna lists 7 ingredients, 7 with an amount per serving of 2 tablets, such as 250 mg of fumitory, 200 mg of dandelion, 200 mg of barberry and 200 mg of artichoke leaf extract. Its current label entered the NIH Dietary Supplement Label Database on August 23, 2013.

What is in HepatoPlex?

Each row as the label prints it, per serving of 2 tablets. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

HepatoPlex: Supplement Facts rows against the market (DSLD label 24419, January 2026 release)
IngredientAmount% DVAmong products listing it
FumitoryFumitory Genus: Fumaria Species: officinalis Note: 4:1 concentrate250 mg
DandelionDandelion PlantPart: root Genus: Taraxacum Species: officinale Note: 4:1 concentrate200 mgDandelion in HepatoPlex against 793 products200 mg per serving; the middle half of products list 50 mg to 250 mg, the median 100 mg.200 mg

Higher than 63% of 793 products listing dandelion (median 100 mg). Per day at the most servings: 400 mg.

BarberryBarberry PlantPart: Root Genus: Berberis Species: vulgaris Note: 3:1 concentrate200 mgBarberry in HepatoPlex against 138 products200 mg per serving; the middle half of products list 30 mg to 200 mg, the median 75 mg.200 mg

Higher than 71% of 138 products listing barberry (median 75 mg). Per day at the most servings: 400 mg.

Artichoke leaf extractArtichoke leaf extract PlantPart: leaf Genus: Cynara Species: scolymus Note: 4:1 concentrate200 mgArtichoke in HepatoPlex against 433 products200 mg per serving; the middle half of products list 50 mg to 250 mg, the median 100 mg.200 mg

Higher than 67% of 433 products listing artichoke (median 100 mg). Per day at the most servings: 400 mg.

Milk Thistleas Silymarin or Silymarin flavonoidsMilk Thistle (Form: standardized extract providing 80% Silymarin or Silymarin flavonoids) Genus: Silybum Species: marianum250 mgMilk Thistle in HepatoPlex against 1,277 products250 mg per serving; the middle half of products list 90 mg to 300 mg, the median 175 mg.250 mg

Higher than 62% of 1,277 products listing milk thistle (median 175 mg). Per day at the most servings: 500 mg.

DL-Methionine200 mgDL-Methionine in HepatoPlex against 151 products200 mg per serving; the middle half of products list 25 mg to 132.5 mg, the median 50 mg.200 mg

Higher than 86% of 151 products listing DL-methionine (median 50 mg). Per day at the most servings: 400 mg.

Betaineas {betaine} citrate complex200 mgBetaine in HepatoPlex against 731 products200 mg per serving; the middle half of products list 50 mg to 1,250 mg, the median 250 mg.200 mg

51% of 731 products listing betaine give more (median 250 mg). Per day at the most servings: 400 mg.

Source: NIH ODS Dietary Supplement Label Database, label 24419 (entered August 23, 2013), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with HepatoPlex's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested use for adults: Two tablets twice daily, away from meals, or as directed by your health care practitioner.
Allergens and what it does not contain
This product contains no yeast, wheat, soy, corn, milk, salt, sugar, artificial coloring, preservatives or flavoring.
Storage
Keep in a cool, dry place, tightly capped.

Source: label statements in DSLD label 24419.

What else is on the label?

Other ingredients: Magnesium Stearate, Stearic Acid, Silicon Dioxide, Cellulose, Dicalcium Phosphate.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): KARUNA(R) RESPONSIBLE NUTRITION(TM).

How many labels does HepatoPlex have?

One label is on file, entered on August 23, 2013.

  1. Label 24419 (current) Entered August 23, 2013 · on the market · 120 tablets

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Karuna Corporation (manufacturer), Novato, CA. All Karuna products.

Where next?