PlainVitamins

Hepagen

by Cardiovascular Research · capsule · 60 capsules

  • On the market (NIH)
  • UPC 6 96859 13184 4
  • DSLD label 304390
  • Serving 1 to 2 capsules; amounts per 1 capsule
  • 60 servings

Hepagen by Cardiovascular Research lists 8 ingredients, 8 with an amount per serving of 1 capsule, such as 3.75 mg of thiamine, 150 mg of milk thistle extract, 100 mg of liver, freeze-dried and 40 mg of alpha-ketoglutarate. Its current label entered the NIH Dietary Supplement Label Database on April 23, 2024.

What is in Hepagen?

Each row as the label prints it, per serving of 1 capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Hepagen: Supplement Facts rows against the market (DSLD label 304390, January 2026 release)
IngredientAmount% DVAmong products listing it
Thiamineas Thiamine Tetrahydrofurfuryl Disulfide3.75 mg250%Thiamin in Hepagen against 9,830 products8.75 mg per serving; the middle half of products list 1.5 mg to 25 mg, the median 5 mg.DV 1.2 mg8.75 mg

Higher than 58% of 9,830 products listing thiamin (median 5 mg).

Milk Thistle extractas Silymarin80% Silymarin150 mgMilk Thistle in Hepagen against 1,277 products150 mg per serving; the middle half of products list 90 mg to 300 mg, the median 175 mg.150 mg

56% of 1,277 products listing milk thistle give more (median 175 mg).

Liver, Freeze-Dried100 mgLiver in Hepagen against 221 products100 mg per serving; the middle half of products list 50 mg to 1,000 mg, the median 250 mg.100 mg

58% of 221 products listing liver give more (median 250 mg).

Alpha-Ketoglutarate40 mgAlpha-Ketoglutarate in Hepagen against 51 products40 mg per serving; the middle half of products list 50 mg to 300 mg, the median 150 mg.40 mg

80% of 51 products listing alpha-ketoglutarate give more (median 150 mg).

N-Acetyl-L-Cysteine30 mgN-Acetyl Cysteine in Hepagen against 1,259 products30 mg per serving; the middle half of products list 55 mg to 500 mg, the median 150 mg.30 mg

88% of 1,259 products listing N-acetyl cysteine give more (median 150 mg).

Lipoic Acid15 mgAlpha Lipoic Acid in Hepagen against 2,407 products15 mg per serving; the middle half of products list 25 mg to 150 mg, the median 50 mg.15 mg

82% of 2,407 products listing alpha lipoic acid give more (median 50 mg).

Dandelion6.5 mgDandelion in Hepagen against 793 products6.5 mg per serving; the middle half of products list 50 mg to 250 mg, the median 100 mg.6.5 mg

97% of 793 products listing dandelion give more (median 100 mg).

Thiamine Tetrahydrofurfuryl Disulfide5 mg

Source: NIH ODS Dietary Supplement Label Database, label 304390 (entered April 23, 2024), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 97% of the 793 products that print an amount of dandelion list more than its 6.5 mg of dandelion (median 100 mg).

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Hepagen's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions Take one or two capsules per day, or as directed by a physician.
Allergens and what it does not contain
This is free of corn, soy, yeast, wheat, egg, milk and other common food allergens.
Gluten free, casein free

Source: label statements in DSLD label 304390.

What else is on the label?

Other ingredients: Gelatin, Garbanzo Bean Flour, Silicon Dioxide.

How many labels does Hepagen have?

4 labels are on file under this name since July 25, 2013: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 304390 (current) Entered April 23, 2024 · on the market · 60 capsules · UPC 6 96859 13184 4
  2. Label 283433 Entered March 22, 2023 · off the market December 22, 2022 · 60 capsules
  3. Label 271160 Entered July 21, 2022 · off the market June 20, 2022 · 60 capsules
  4. Label 22574 Entered July 25, 2013 · off the market December 14, 2021 · 60 capsules

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Cardiovascular Research, LTD. (distributor), Concord, CA. All Cardiovascular Research products.

Where next?