PlainVitamins

Heartburn Advantage

by Integrative Therapeutics · capsule · 60 capsules

  • On the market (NIH)
  • UPC 8 71791 11013 7
  • DSLD label 288694
  • Serving 1 capsule
  • 60 servings

Heartburn Advantage by Integrative Therapeutics lists 5 ingredients, 5 with an amount per serving of 1 capsule, such as 16 mg of zinc, 75 mg of GutGard deglycyrrhizinated licorice (DGL) (glycyrrhiza spp.) root extract and 75 mg of zinc-carnosine. Its current label entered the NIH Dietary Supplement Label Database on August 24, 2023.

What is in Heartburn Advantage?

Each row as the label prints it, per serving of 1 capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Heartburn Advantage: Supplement Facts rows against the market (DSLD label 288694, January 2026 release)
IngredientAmount% DVAmong products listing it
Zincas Zinc CarnosineZinc (Form: as Zinc-Carnosine)16 mg145%Zinc in Heartburn Advantage against 13,186 products16 mg per serving; the middle half of products list 5 mg to 15 mg, the median 11 mg.DV 11 mgUL 40 mg16 mg

Higher than 78% of 13,186 products listing zinc (median 11 mg). Per day at the most servings: 32 mg.

Clinically Studied Proprietary Blend120 mg
Pycrinil Artichoke (Cynara cardunculus) leaf extract100 mgArtichoke in Heartburn Advantage against 433 products100 mg per serving; the middle half of products list 50 mg to 250 mg, the median 100 mg.100 mg

46% of 433 products listing artichoke give more (median 100 mg). Per day at the most servings: 200 mg.

Ginger (zingiber officinale) root extract20 mgGinger in Heartburn Advantage against 1,770 products20 mg per serving; the middle half of products list 25 mg to 150 mg, the median 60 mg.20 mg

77% of 1,770 products listing ginger give more (median 60 mg). Per day at the most servings: 40 mg.

GutGard Deglycyrrhizinated Licorice (DGL) (Glycyrrhiza spp.) root extract75 mgLicorice in Heartburn Advantage against 888 products75 mg per serving; the middle half of products list 42 mg to 300 mg, the median 100 mg.75 mg

52% of 888 products listing licorice give more (median 100 mg). Per day at the most servings: 150 mg.

Zinc-Carnosine75 mgZinc-l-Carnosine in Heartburn Advantage against 36 products75 mg per serving; the middle half of products list 34.38 mg to 75 mg, the median 75 mg.75 mg

6% of 36 products listing zinc-l-carnosine give more (median 75 mg). Per day at the most servings: 150 mg.

Source: NIH ODS Dietary Supplement Label Database, label 288694 (entered August 24, 2023), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Heartburn Advantage's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommendation: Adults take 1 capsule in the morning after food, and 1 capsule in the evening after food, or as recommended by a healthcare professional. Do not exceed recommended dose.
Warnings
Keep out of reach of children.
Safety sealed with inner seal. Do not use if seal is broken or missing.
Warning: Do not use if you have a bile duct obstruction, or if you are allergic to plants of the Asteraceae (Compositae) family, including ragweed.
If you are pregnant, nursing, have gallstones, or if you are taking prescription drugs, consult a healthcare professional before use.
Allergens and what it does not contain
Contains no wheat, gluten, soy, dairy, or artificial colors, flavors, or preservatives.
Storage
Store at room temperature. Avoid excessive heat and direct sunlight.

Source: label statements in DSLD label 288694.

What else is on the label?

Other ingredients: Dicalcium Phosphate, Cellulose, Hypromellose, Sodium Croscarmellose, Silica, Magnesium Stearate.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Quality Global Sourcing Bottled & Tested in the USA.

How many labels does Heartburn Advantage have?

2 labels are on file under this name since June 24, 2020: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 288694 (current) Entered August 24, 2023 · on the market · 60 capsules · UPC 8 71791 11013 7
  2. Label 223290 Entered June 24, 2020 · off the market April 4, 2022 · 60 veg capsules · UPC 8 71791 11013 7

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Integrative Therapeutics, LLC (manufacturer), Green Bay, WI. All Integrative Therapeutics products.

Where next?