HCl + Enzymes

by Smidge · capsule · 120 capsules

  • On the market (NIH)
  • UPC 8 50019 90201 3
  • DSLD label 337911
  • Serving 1 to 2 capsules; amounts per 2 capsules
  • 60 servings

HCl + Enzymes by Smidge lists 6 ingredients, 2 with an amount per serving of 2 capsules, such as 400 mg of betaine hydrochloride and 8 mg of pepsin; 4 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on September 25, 2025.

What is in HCl + Enzymes?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

HCl + Enzymes: Supplement Facts rows against the market (DSLD label 337911, January 2026 release)
IngredientAmount% DVAmong products listing it
Betaine Hydrochloride400 mgBetaine Hydrochloride in HCl + Enzymes against 914 products400 mg per serving; the middle half of products list 25 mg to 178 mg, the median 50 mg.400 mg

Higher than 86% of 914 products listing betaine hydrochloride (median 50 mg).

Pepsin8 mgPepsin in HCl + Enzymes against 223 products8 mg per serving; the middle half of products list 25 mg to 130 mg, the median 50 mg.8 mg

91% of 223 products listing pepsin give more (median 50 mg).

Comprehensive Enzyme Blend494 mg
Lipasein the blend, no amount given
Amylasein the blend, no amount given
Protease Peptidase Complexin the blend, no amount given
Lactasein the blend, no amount given
Phytasein the blend, no amount given

Source: NIH ODS Dietary Supplement Label Database, label 337911 (entered September 25, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 91% of the 223 products that print an amount of pepsin list more than its 8 mg of pepsin (median 50 mg).

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with HCl + Enzymes's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested use: Start with 1 capsule daily with food. Then take two capsules together, or as directed by a practitioner.
Warnings
Do not use if the safety seal is broken or missing.
Keep out of reach of children.
Do not chew or open capsules. Do not take on an empty stomach.
HCl should not be taken if you have stomach or duodenal ulcers or are taking drugs that may cause ulcers.
Allergens and what it does not contain
Free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans. No artificial colors, flavors, or preservatives.
Storage
Storage: Store in a cool, dry place.

Source: label statements in DSLD label 337911.

What else is on the label?

Other ingredients: Cellulose, Hydroxypropyl Methylcellulose, Water.

How many labels does HCl + Enzymes have?

One label is on file, entered on September 25, 2025.

  1. Label 337911 (current) Entered September 25, 2025 · on the market · 120 capsules · UPC 8 50019 90201 3

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Organic 3, Inc. (distributor), Southfield, MI. All Smidge products.

Where next?