HCL Breakthrough

by BiOptimizers · capsule · 90 veggie caps

  • On the market (NIH)
  • UPC 0 648620 408426
  • DSLD label 320984
  • Serving 1 capsule
  • 90 servings

HCL Breakthrough by BiOptimizers lists 6 ingredients, 1 with an amount per serving of 1 capsule, such as 500 mg of betaine hydrochloride; 4 give their count of live cultures or enzyme activity instead of a weight; 1 sits inside a blend without its own amount. Its current label entered the NIH Dietary Supplement Label Database on November 22, 2024.

What is in HCL Breakthrough?

Each row as the label prints it, per serving of 1 capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

HCL Breakthrough: Supplement Facts rows against the market (DSLD label 320984, January 2026 release)
IngredientAmount% DVAmong products listing it
Betaine Hydrochloride500 mgBetaine Hydrochloride in HCL Breakthrough against 914 products500 mg per serving; the middle half of products list 25 mg to 178 mg, the median 50 mg.500 mg

Higher than 89% of 914 products listing betaine hydrochloride (median 50 mg).

Enzyme Blend21.5 mg
Protease 325 SAPUin the blend, no amount given
Protease 4.52,500 HUT
Amylase625 SKB
Lipase750 FIP
Cellulase750 CU
Trace Mineral5 mg

Source: NIH ODS Dietary Supplement Label Database, label 320984 (entered November 22, 2024), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient; 5 ingredients sit inside a blend, so their amounts cannot be compared.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with HCL Breakthrough's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: Take 1 capsule with each meal, or within 30 minutes of eating a meal.
Warnings
Caution: Keep out of reach of children.
Do not use if ulcer or gastritis are present. As with any product, discontinue immediately if adverse effects occur. Please consult a physician before beginning any new supplement, diet, training program, or if you are undergoing treatment of a medical condition.
Allergens and what it does not contain
Gluten-free Soy-free
Storage
Store in a cool/dry location.

Source: label statements in DSLD label 320984.

What else is on the label?

Other ingredients: Rice Extract, Cellulose, Water.

How many labels does HCL Breakthrough have?

2 labels are on file under this name since February 21, 2023: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 320984 (current) Entered November 22, 2024 · on the market · 90 veggie caps · UPC 0 648620 408426
  2. Label 284043 Entered February 21, 2023 · off the market December 14, 2023 · 90 caps · UPC 0 648620 408426

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names BiOptimizers USA, Inc. (distributor), Reno, NV. All BiOptimizers products.

Where next?