PlainVitamins

GI-One

by Patient One 1 MediNutritionals · capsule · 180 vegetable capsules

  • On the market (NIH)
  • UPC 8 53959 00433 5
  • DSLD label 276256
  • Serving 1 to 2 capsules; amounts per 1 capsule
  • 180 servings

GI-One by Patient One 1 MediNutritionals lists 14 ingredients, 11 with an amount per serving of 1 capsule, such as 35 mg of amylase, 100 mg of bromelain, 50 mg of betaine hydrochloride and 40 mg of cellulase; 3 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on October 24, 2022.

What is in GI-One?

Each row as the label prints it, per serving of 1 capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

GI-One: Supplement Facts rows against the market (DSLD label 276256, January 2026 release)
IngredientAmount% DVAmong products listing it
Amylaseas Aspergillus oryzae100,000 FCC units/gm35 mgAmylase in GI-One against 326 products35 mg per serving; the middle half of products list 5 mg to 50 mg, the median 14 mg.35 mg

Higher than 67% of 326 products listing amylase (median 14 mg).

Bromelainas Pineapple2400 Gelatin Digestive Units per gram100 mgBromelain in GI-One against 1,337 products100 mg per serving; the middle half of products list 25 mg to 200 mg, the median 50 mg.100 mg

Higher than 55% of 1,337 products listing bromelain (median 50 mg).

Betaine Hydrochloride50 mgBetaine Hydrochloride in GI-One against 914 products50 mg per serving; the middle half of products list 25 mg to 178 mg, the median 50 mg.50 mg

47% of 914 products listing betaine hydrochloride give more (median 50 mg).

Cellulaseas Trichoderma20,000 FCC units/gram40 mgCellulase in GI-One against 184 products40 mg per serving; the middle half of products list 3.74 mg to 30 mg, the median 10 mg.40 mg

Higher than 84% of 184 products listing cellulase (median 10 mg).

Lipaseas Aspergillus nigerLipase (Form: Aspergillus niger Genus: Aspergillus Species: niger) Note: 100,000 FIP LU/gm5 mgLipase in GI-One against 366 products5 mg per serving; the middle half of products list 5 mg to 25 mg, the median 10 mg.5 mg

68% of 366 products listing lipase give more (median 10 mg).

Lactaseas Aspergillus oryzaeLactase (Form: Aspergillus oryzae Genus: Aspergillus Species: oryzae) Note: 100,000 FCC/gm10 mgLactase in GI-One against 138 products10 mg per serving; the middle half of products list 10 mg to 197.5 mg, the median 34 mg.10 mg

73% of 138 products listing lactase give more (median 34 mg).

Lactosporeas Lactobacillus sporogenes15 billion/gram (Providing 166.5 million spores)11.1 mg
Papaya powder100 mgPapaya in GI-One against 250 products100 mg per serving; the middle half of products list 25 mg to 150 mg, the median 50 mg.100 mg

Higher than 62% of 250 products listing papaya (median 50 mg).

Papainas Carica papayaPapain (Form: Carica papaya PlantPart: fruit Genus: Carica Species: papaya) Note: 2000 USP units/mg9 mgPapain in GI-One against 607 products9 mg per serving; the middle half of products list 20 mg to 75 mg, the median 40 mg.9 mg

87% of 607 products listing papain give more (median 40 mg).

Pancreatin 4Xas Porcine200 mg
Protease100 USP units/mgin the blend, no amount given
Amylase100 USP units/mgin the blend, no amount given
Lipase8 USP units/mgin the blend, no amount given
Proteaseas Aspergillus niger200,000 FCC units/gm3.25 mgProteolytic Enzymes (Proteases) in GI-One against 327 products3.25 mg per serving; the middle half of products list 10 mg to 100 mg, the median 30 mg.3.25 mg

91% of 327 products listing proteolytic enzymes (proteases) give more (median 30 mg).

Quercetinas Quercetin Dihydrate37.5 mgQuercetin in GI-One against 1,548 products37.5 mg per serving; the middle half of products list 26.5 mg to 250 mg, the median 100 mg.37.5 mg

69% of 1,548 products listing quercetin give more (median 100 mg).

Source: NIH ODS Dietary Supplement Label Database, label 276256 (entered October 24, 2022), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 91% of the 327 products that print an amount of proteolytic enzymes (proteases) list more than its 3.25 mg of proteolytic enzymes (proteases) (median 30 mg).

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with GI-One's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Use: Take 1 capsule at the start of afternoon and evening meals as a dietary supplement, or as directed by a health practitioner. May take an additional capsule with each meal as needed.
Warnings
Caution: If you are pregnant, nursing, or taking any medications, consult your health practitioner before use.
Discontinue use and consult your health practitioner if any adverse reactions occur.
Keep out of reach of children.
Use only if safety seal is intact.
Allergens and what it does not contain
Gluten free Non-GMO Free of: Milk, egg, fish, peanuts, crustacean shellfish, soy, tree nuts, wheat, yeast and gluten. Free of ingredients derived from GMOs.

Source: label statements in DSLD label 276256.

What else is on the label?

Other ingredients: Cellulose, Rice Flour, Leucine.

How many labels does GI-One have?

2 labels are on file under this name since July 24, 2015: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 276256 (current) Entered October 24, 2022 · on the market · 180 vegetable capsules · UPC 8 53959 00433 5
  2. Label 48015 Entered July 24, 2015 · off the market January 23, 2018 · 180 vegetable capsules · UPC 8 53959 00433 5

DSLD also links this label to: GI-One (package size difference, same product), GI-One (image difference, same product), GI-One (package size difference, same product), GI-One (package size difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names MediNutritionals Research LLC (manufacturer, distributor), Hauppage, NY. All Patient One 1 MediNutritionals products.

Where next?