PlainVitamins

Fibrinex

by HoltraCeuticals · capsule · 120 capsules

  • On the market (NIH)
  • UPC 8 37654 69371 1
  • DSLD label 270843
  • Serving 1 capsule
  • 120 servings

Fibrinex by HoltraCeuticals lists 5 ingredients, 5 with an amount per serving of 1 capsule, such as 500 mg of bromelain, powder, 50 mg of nattokinase, powder, 20 mg of lumbrokinase, powder and 15 mg of serratiopeptidase, powder. Its current label entered the NIH Dietary Supplement Label Database on July 21, 2022.

What is in Fibrinex?

Each row as the label prints it, per serving of 1 capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Fibrinex: Supplement Facts rows against the market (DSLD label 270843, January 2026 release)
IngredientAmount% DVAmong products listing it
Bromelain, Powderas Pineapple2400 GDU/g500 mgBromelain in Fibrinex against 1,337 products500 mg per serving; the middle half of products list 25 mg to 200 mg, the median 50 mg.500 mg

Higher than 90% of 1,337 products listing bromelain (median 50 mg).

Nattokinase, Powder20,000 FU/g50 mgNattokinase in Fibrinex against 141 products50 mg per serving; the middle half of products list 50 mg to 100 mg, the median 100 mg.50 mg

67% of 141 products listing nattokinase give more (median 100 mg).

Lumbrokinase, Powder20,000 U/mg20 mg
Serratiopeptidase, Powder2400 SPU/mg15 mgSerratiopeptidase in Fibrinex against 64 products15 mg per serving; the middle half of products list 16.25 mg to 74.25 mg, the median 33 mg.15 mg

75% of 64 products listing serratiopeptidase give more (median 33 mg).

Alpha-Chymotrypsin, Powderas Porcine1500 U/mg15 mgChymotrypsin in Fibrinex against 49 products15 mg per serving; the middle half of products list 2 mg to 5 mg, the median 3 mg.15 mg

Higher than 88% of 49 products listing chymotrypsin (median 3 mg).

Source: NIH ODS Dietary Supplement Label Database, label 270843 (entered July 21, 2022), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Fibrinex's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested use: As a dietary supplement, take one (1) capsule per day on an empty stomach.
Warnings
Warning: If you are under medical supervision, seek the advice of your physician or healthcare professional prior to use of this product.
Individuals with autoimmune conditions, depressive disorders or pregnant/lactating women should consult their physician prior to use.
Keep out of reach of children.
Do not use if safety seal is damaged or missing.
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 270843.

What else is on the label?

Other ingredients: Gelatin Capsule, Magnesium Stearate, Rice Flour.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): GMP Good Manufacturing Practice; Made in USA.

How many labels does Fibrinex have?

2 labels are on file under this name since March 25, 2013: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 270843 (current) Entered July 21, 2022 · on the market · 120 capsules · UPC 8 37654 69371 1
  2. Label 19417 Entered March 25, 2013 · off the market November 23, 2021 · 120 capsules · UPC 8 37654 69371 1

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Holtorf Medical Group (distributor), El Segundo, CA. All HoltraCeuticals products.

Where next?