EsophaCool

by Life Extension · tablet or pill · 60 chewable tablets

  • On the market (NIH)
  • UPC 7 37870 20336 0
  • DSLD label 232679
  • Serving 2 tablets
  • 30 servings

EsophaCool by Life Extension lists 3 ingredients, 3 with an amount per serving of 2 tablets, such as 200 mg of calcium, 200 mg of magnesium and 75 mg of GutGard deglycyrrhizinated licorice (DGL) extract. Its current label entered the NIH Dietary Supplement Label Database on August 23, 2020.

What is in EsophaCool?

Each row as the label prints it, per serving of 2 tablets. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

EsophaCool: Supplement Facts rows against the market (DSLD label 232679, January 2026 release)
IngredientAmount% DVAmong products listing it
CalciumCalcium (Form: From 500 mg Calcium Carbonate)200 mg15%Calcium in EsophaCool against 17,831 products200 mg per serving; the middle half of products list 50 mg to 252 mg, the median 115 mg.DV 1,300 mgUL 2,500 mg200 mg

Higher than 64% of 17,831 products listing calcium (median 115 mg). Per day at the most servings: 600 mg.

MagnesiumMagnesium (Form: from 800 mg Magnesium Carbonate)200 mg48%Magnesium in EsophaCool against 14,003 products200 mg per serving; the middle half of products list 30 mg to 200 mg, the median 86 mg.UL 350 mgDV 420 mg200 mg

Higher than 75% of 14,003 products listing magnesium (median 86 mg). Per day at the most servings: 600 mg. 1.7 times the adult UL a day.

GutGard Deglycyrrhizinated Licorice (DGL) extractas Total FlavonoidsGutGard Deglycyrrhizinated Licorice (DGL) extract (Form: std. to greater than or equal to 10% Total Flavonoids) (Alt. Name: DGL) PlantPart: root75 mgLicorice in EsophaCool against 888 products75 mg per serving; the middle half of products list 42 mg to 300 mg, the median 100 mg.75 mg

52% of 888 products listing licorice give more (median 100 mg). Per day at the most servings: 225 mg.

Source: NIH ODS Dietary Supplement Label Database, label 232679 (entered August 23, 2020), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • At 3 servings a day, the most its directions give, the label lists 600 mg of magnesium, 1.7 times the adult Tolerable Upper Intake Level.

The NIH database records 2 to 3 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

1 product lists the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Read the entire label and follow the directions carefully prior to use. Directions: Chew two (2) tablets two to three times daily as needed, or as recommended by a healthcare practitioner. Do not swallow tablets whole.
Warnings
Do not swallow tablets whole. Caution: If taken in high doses, magnesium may have a laxative effect.
Warnings: Keep out of reach of children.
Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
To report a serious adverse event or obtain product information, contact 1-866-280-2852.
Allergens and what it does not contain
Non GMO LE Certified
Storage
Store tightly closed in a cool, dry place.

Source: label statements in DSLD label 232679.

What else is on the label?

Other ingredients: Xylitol, Mannitol, Flavors, Microcrystalline Cellulose, Stearic Acid, Dextrin, Citric Acid, Croscarmellose Sodium, Gum Arabic, Silica, Vegetable Stearate, Stevia extract.

How many labels does EsophaCool have?

7 labels are on file under this name since May 24, 2017: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 232679 (current) Entered August 23, 2020 · on the market · 60 chewable tablets · UPC 7 37870 20336 0
  2. Label 232312 Entered August 23, 2020 · off the market August 9, 2023 · 60 chewable tablets · UPC 7 37870 20331 5
  3. Label 182350 Entered October 25, 2018 · off the market July 14, 2020 · 60 chewable tablets · UPC 7 37870 20331 5
  4. Label 182348 Entered October 25, 2018 · off the market July 14, 2020 · 60 chewable tablets · UPC 7 37870 20336 0
  5. Label 74317 Entered May 24, 2017 · on the market · 120 chewable tablets · UPC 7 37870 20090 1
  6. Label 74311 Entered May 24, 2017 · on the market · 120 chewable tablets · UPC 7 37870 20091 8
  7. Label 74305 Entered May 24, 2017 · off the market October 21, 2016 · 120 chewable tablets · UPC 7 37870 20091 8

DSLD also links this label to: EsophaCool Berry Flavor (alternate version).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Quality Supplements and Vitamins, Inc. (distributor), Ft. Lauderdale, FL. All Life Extension products.

Where next?