PlainVitamins

Enzyme Defense

by Enzyme Science · capsule · 60 capsules

  • Off the market since January 2025 (NIH)
  • UPC 6 70480 30020 6
  • DSLD label 22625
  • Serving 1 capsule
  • 60 servings

Enzyme Defense by Enzyme Science lists 7 ingredients, 7 with an amount per serving of 1 capsule, such as 1,000 IU (25 mcg) of vitamin D3, 350,000 HUT of protease, 100 Baker of catalase and 800 FU of nattokinase. Its current label entered the NIH Dietary Supplement Label Database on July 25, 2013.

What is in Enzyme Defense?

Each row as the label prints it, per serving of 1 capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Enzyme Defense: Supplement Facts rows against the market (DSLD label 22625, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin D31,000 IU (25 mcg)125%*Vitamin D in Enzyme Defense against 14,175 products25 mcg per serving; the middle half of products list 10 mcg to 25 mcg, the median 15 mcg.DV 20 mcgUL 100 mcg25 mcg

Higher than 59% of 14,175 products listing vitamin D (median 15 mcg).

Minerals65 mg
ProteaseProtease Thera-blend350,000 HUT
Catalase100 Baker
NattokinaseNattokinase Blend800 FU
Serratiopeptidase50,000 SPU
Mucolase16 mg
L-Lysine10 mgLysine in Enzyme Defense against 1,250 products10 mg per serving; the middle half of products list 148.25 mg to 996.25 mg, the median 500 mg.10 mg

97% of 1,250 products listing lysine give more (median 500 mg).

* % Daily Value computed from the printed amount and the FDA Daily Value (21 CFR 101.9); the label prints none for that row.

Source: NIH ODS Dietary Supplement Label Database, label 22625 (entered July 25, 2013), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 97% of the 1,250 products that print an amount of lysine list more than its 10 mg of L-lysine (filed by NIH under lysine) (median 500 mg).

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Enzyme Defense's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommended Usage: Take 1 per day on an empty stomach (1/2 hour before or 2 hours after a meal). More may be taken as recommended by your healthcare practitioner.*
Warnings
Consult a physician if pregnant or lactating.
AS WITH ALL PRODUCTS, PLEASE KEEP OUT OF REACH OF CHILDREN
Allergens and what it does not contain
ABSOLUTELY NO FILLERS ADDED
CONTAINS NO: Dairy, preservatives, salt, sucrose, soy, wheat, yeast, nuts, corn, gluten, casein, potato, rice, artificial colors or flavors.
Storage
Keep closed in dry place; avoid excessive heat.

Source: label statements in DSLD label 22625.

What else is on the label?

Other ingredients: 100% Vegetarian Capsule.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): vitamin angels; AUTISM HOPE ALLIANCE AHA; VERIFIED BeGreen.

How many labels does Enzyme Defense have?

One label is on file, entered on July 25, 2013.

  1. Label 22625 (current) Entered July 25, 2013 · off the market January 28, 2025 · 60 capsules · UPC 6 70480 30020 6

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Enzyme Science (manufacturer), Port Charlotte, FL. All Enzyme Science products.

Where next?