PlainVitamins

Endorphinate PR

by Pondera · capsule · 60 vegetarian capsules

  • On the market (NIH)
  • UPC 6 10373 94736 1
  • DSLD label 178260
  • Serving 1 vegetarian capsule
  • 60 servings

Endorphinate PR by Pondera lists 14 ingredients, 9 with an amount per serving of 1 vegetarian capsule, such as 5 mg of vitamin B6, 200 mcg of folate, 50 mcg of vitamin B12 and 5 mg of magnesium; 5 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on June 25, 2018.

What is in Endorphinate PR?

Each row as the label prints it, per serving of 1 vegetarian capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Endorphinate PR: Supplement Facts rows against the market (DSLD label 178260, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin B65 mg250%Vitamin B6 in Endorphinate PR against 15,277 products5 mg per serving; the middle half of products list 2 mg to 20 mg, the median 6 mg.DV 1.7 mgUL 100 mg5 mg

51% of 15,277 products listing vitamin B6 give more (median 6 mg). Per day at the most servings: 10 mg.

Pyridoxal 5-Phosphate5 mg
Folate200 mcg50%Folate in Endorphinate PR against 7,022 products200 mcg per serving; the middle half of products list 200 mcg to 400 mcg, the median 400 mcg.200 mcg

71% of 7,022 products listing folate give more (median 400 mcg). Per day at the most servings: 400 mcg.

Folic Acid200 mcg
Vitamin B1250 mcg833%Vitamin B12 in Endorphinate PR against 14,425 products50 mcg per serving; the middle half of products list 6 mcg to 200 mcg, the median 36 mcg.DV 2.4 mcg50 mcg

Higher than 51% of 14,425 products listing vitamin B12 (median 36 mcg). Per day at the most servings: 100 mcg.

Methylcobalamin50 mcg
Magnesium5 mg1%Magnesium in Endorphinate PR against 14,003 products5 mg per serving; the middle half of products list 30 mg to 200 mg, the median 86 mg.UL 350 mgDV 420 mg5 mg

96% of 14,003 products listing magnesium give more (median 86 mg). Per day at the most servings: 10 mg.

Magnesium Sulfate50 mg
Proprietary Blend780 mg
White Willowin the blend, no amount given
N-Acetyl Cysteinein the blend, no amount given
Guarana Extractin the blend, no amount given
L-Theaninein the blend, no amount given
Boswellia extractin the blend, no amount given
Caffeine60 mgCaffeine in Endorphinate PR against 3,358 products60 mg per serving; the middle half of products list 100 mg to 275 mg, the median 200 mg.60 mg

89% of 3,358 products listing caffeine give more (median 200 mg). Per day at the most servings: 120 mg.

Source: NIH ODS Dietary Supplement Label Database, label 178260 (entered June 25, 2018), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 96% of the 14,003 products that print an amount of magnesium list more than its 5 mg of magnesium (median 86 mg).

The NIH database records 1 to 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Endorphinate PR's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Use. Take one capsule one to two times daily with or without food.
Warnings
Warnings. Keep out of reach of children.
Do not purchase if seal is broken or missing.
Please consult your health care practitioner before taking this product with regard to any questions you may have or if you are pregnant, nursing, taking any medication, or have a medical condition.
Allergens and what it does not contain
This product contains no artificial sweeteners, flavors, colors, or preservatives
Storage
Protect from heat, light and moisture. Store tightly in a cool, dry place.

Source: label statements in DSLD label 178260.

What else is on the label?

Other ingredients: Vegetable Cellulose, Rice Bran, Ascorbyl Palmitate.

How many labels does Endorphinate PR have?

2 labels are on file under this name since June 25, 2013: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 178260 (current) Entered June 25, 2018 · on the market · 60 vegetarian capsules · UPC 6 10373 94736 1
  2. Label 22851 Entered June 25, 2013 · off the market January 19, 2018 · 60 vegetarian capsules

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Pondera Pharmaceuticals, Inc. (distributor), Pownal, ME. All Pondera products.

Where next?